acstop soap allopathy (Clindamycin (1%) + Nicotinamide (0.5%)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acstop soap allopathy (Clindamycin (1%) + Nicotinamide (0.5%)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Sol Derma Pharmaceuiticals Pvt Ltd. Contains Clindamycin (1%) + Nicotinamide (0.5%).

Acstop Soap - Uses, Price, Side Effects

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🏭 Sol Derma Pharmaceuiticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 20, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acstop soap used for?

Acstop Soap is a medicated soap used to treat acne. It contains Clindamycin, an antibiotic that kills acne-causing bacteria, and Nicotinamide, which reduces inflammation and redness. Regular use helps clear existing acne and prevent new breakouts.

  • Generic Name: Clindamycin + Nicotinamide
  • Manufacturer: Sol Derma Pharmaceuiticals Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acstop soap के बारे में संक्षिप्त जानकारी (Hindi Summary)

acstop soap का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Clindamycin (1%) + Nicotinamide (0.5%) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Clindamycin + Nicotinamide
Brand NameAcnetoin Gel
ManufacturerSol Derma Pharmaceuiticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntibiotic + Vitamin B3 derivative
Route of AdministrationTopical
StorageStore at room temperature (20-25°C), away from moisture and heat.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption is low.
DistributionDistributes locally in skin layers; minimal systemic distribution.
Protein BindingClindamycin: ~94% bound to plasma proteins; Nicotinamide: minimal binding.
MetabolismClindamycin: Hepatic metabolism via CYP3A4; Nicotinamide: Hepatic metabolism to N-methylnicotinamide.
Half-LifeClindamycin: ~2-3 hours; Nicotinamide: ~1-2 hours.
ExcretionClindamycin: Renal and biliary; Nicotinamide: Renal.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionWithin a few days to weeks.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionSustained with regular application.

Pharmacodynamics

Mechanism of ActionClindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Nicotinamide reduces sebum production and has anti-inflammatory effects.
Target ReceptorClindamycin: 50S ribosomal subunit; Nicotinamide: Not receptor-mediated.
Pharmacodynamic EffectsReduction of Propionibacterium acnes, decreased inflammation, and decreased sebum production.

📅 When to take acstop soap?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take acstop soap?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), away from moisture and heat.

⚙️ How acstop soap Works

Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Nicotinamide reduces sebum production and has anti-inflammatory effects.

1 Clindamycin binds to 50S ribosomal subunit of bacteria, inhibiting protein synthesis.
⬇️
2 Nicotinamide inhibits sebocyte lipid synthesis and reduces inflammatory cytokine production.
⬇️
3 Combination reduces P. acnes population and inflammation.

💊 acstop soap Uses in Hindi (Ke Fayde), Benefits & Indications

Acne vulgaris, inflammatory acne.

Off-label uses: Rosacea, perioral dermatitis.

⚠️ What are the side effects of acstop soap?

✅ Common Side Effects

  • Skin dryness
  • Peeling
  • Erythema
  • Burning sensation

🚨 Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions

⚠️ Rare Side Effects

  • Contact dermatitis
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for acstop soap

View All

Alternative medicines with exact same composition and strength (Clindamycin (1%) + Nicotinamide (0.5%)):

  1. acstop soap
    Sol Derma Pharmaceuiticals Pvt Ltd₹49.99💰 Same price

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Erythromycin Moderate Increased risk of antibiotic resistance
Warfarin Minor Possible decreased anticoagulant effect

🚨 Major Interactions

  • Neuromuscular blocking agents
  • Erythromycin

⚡ Moderate Interactions

  • Other topical antibiotics
  • Retinoids

ℹ️ Minor Interactions

  • None significant

🍽️ Food Interactions

None known.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity to clindamycin, nicotinamide, or any component; history of antibiotic-associated colitis.

📊 Monitoring Parameters

Skin irritation, signs of hypersensitivity, improvement in acne lesions.

🤱 Lactation Safety

Clindamycin is excreted in breast milk; use with caution. Nicotinamide is safe.

💊 Overdose Management

Topical overdose unlikely; if ingested, symptomatic and supportive care.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

🛑 Myths vs. Facts about acstop soap

  • Myth: Generic substitutes of acstop soap are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Clindamycin (1%) + Nicotinamide (0.5%)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acstop soap can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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