actame 20mg tablet allopathy (Isotretinoin (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
actame 20mg tablet allopathy (Isotretinoin (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Sol Derma Pharmaceuiticals Pvt Ltd. Contains Isotretinoin (20mg).

actame 20mg tablet - Uses, Price, Side Effects & Substitutes

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Isotretinoin (20mg) (Click to see all medicines with same salt)
🏭 Sol Derma Pharmaceuiticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is actame 20mg tablet used for?

Acutret 10 Capsule (Isotretinoin) is used to treat Severe recalcitrant nodular acne. It contains Isotretinoin (20mg), which Reduces sebum production, normalizes follicular keratinization, inhibits Propion. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Isotretinoin
  • Manufacturer: Sol Derma Pharmaceuiticals Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 actame 20mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

actame 20mg tablet का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Isotretinoin (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

📋 Drug Information

Generic Name(s)Isotretinoin
Brand NameAcutret 10 Capsule
ManufacturerSol Derma Pharmaceuiticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- First generation
Route of AdministrationOral.
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed orally with high bioavailability; absorption enhanced with food.
DistributionExtensively distributed; crosses placenta; enters breast milk.
Protein Binding99.9% bound to albumin.
MetabolismHepatic metabolism via CYP450 enzymes to active metabolites (4-oxo-isotretinoin).
Half-Life20-24 hours for parent drug; longer for metabolites.
ExcretionExcreted in urine and feces equally.
Bioavailability25% (increased with food).
Onset of Action1-2 weeks for initial improvement.
Peak Plasma Time3-4 hours.
Duration of ActionTherapeutic effect persists weeks after discontinuation.

Pharmacodynamics

Mechanism of ActionReduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.
Target ReceptorRetinoic acid receptors (RARs) and retinoid X receptors (RXRs).
Pharmacodynamic EffectsDecreased sebum excretion, reduced comedogenesis, anti-inflammatory, and antimicrobial.

💡 How and when to take actame 20mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How actame 20mg tablet Works

Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.

1 Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in the nucleus.
⬇️
2 Modulates gene transcription involved in cell growth, differentiation, and apoptosis.
⬇️
3 Reduces sebocyte proliferation and sebum production.
⬇️
4 Normalizes follicular keratinization, preventing comedone formation.
⬇️
5 Inhibits Propionibacterium acnes growth indirectly by altering sebum composition.
⬇️
6 Exerts anti-inflammatory effects by inhibiting neutrophil chemotaxis and cytokine production.

💊 actame 20mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.

Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.

⚠️ What are the side effects of actame 20mg tablet?

✅ Common Side Effects

  • Cheilitis
  • Dry skin
  • Xerophthalmia
  • Epistaxis
  • Arthralgia
  • Myalgia
  • Headache
  • Increased triglycerides

🚨 Serious Side Effects

  • Pseudotumor cerebri
  • Hepatotoxicity
  • Pancreatitis
  • Depression/suicidal ideation
  • Inflammatory bowel disease
  • Teratogenicity

⚠️ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Vasculitis
  • Hearing impairment
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for actame 20mg tablet

View All

Alternative brands with exact same active ingredient and strength (Isotretinoin (20mg)):

  1. actinin o 20mg soft gelatin capsule
    Zeelab Pharmacy Pvt Ltd₹36.00💰 82.6% CHEAPER
  2. davaindia isotretinoin 20mg capsule
    Davaindia Generic Pharmacy₹42.00💰 79.7% CHEAPER
  3. aczit 20mg capsule
    Canixa Life Sciences Pvt₹108.17💰 47.8% CHEAPER
  4. stayhappi isotretinoin 20mg capsule
    Sarvagunaushdhi Pvt Ltd₹108.89💰 47.4% CHEAPER
  5. doin 20mg soft gelatin capsule
    Ultratech Pharmaceuticals₹117.19💰 43.4% CHEAPER
  6. face 20mg capsule
    Bonsai Pharma₹120.00💰 42.1% CHEAPER
  7. ivotex 20mg tablet
    Zee Laboratories₹120.00💰 42.1% CHEAPER
  8. treticure 20mg capsule
    Cure Quick Pharmaceuticals₹120.00💰 42.1% CHEAPER
  9. tretimax 20 tablet
    Invision Medi Sciences Pvt Ltd₹124.60💰 39.9% CHEAPER
  10. isotriti 20mg soft gelatin capsule
    Andee Lifesciences₹125.00💰 39.7% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Tetracyclines Major Increased risk of pseudotumor cerebri
Vitamin A supplements Major Additive toxicity (hypervitaminosis A)
Methotrexate Major Increased hepatotoxicity risk
Oral contraceptives Major Reduced contraceptive efficacy
Phenytoin Moderate Increased phenytoin levels
Corticosteroids Moderate Increased osteoporosis risk
Azole antifungals Moderate Increased retinoid toxicity
Alcohol Minor Increased hepatotoxicity risk
Antacids Minor Reduced isotretinoin absorption

🚨 Major Interactions

  • Tetracyclines
  • Vitamin A supplements
  • Methotrexate
  • Oral contraceptives (reduced efficacy)

⚡ Moderate Interactions

  • Phenytoin
  • Corticosteroids
  • Antifungals (azole)

ℹ️ Minor Interactions

  • Alcohol
  • Antacids

🍽️ Food Interactions

High-fat meals increase absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.

📊 Monitoring Parameters

Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🛑 Myths vs. Facts about actame 20mg tablet

  • Myth: Generic substitutes of actame 20mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Isotretinoin (20mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of actame 20mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Log mujhe bhoot samajh rahe hain! Safed daag ka stigma khatam kaise karein?

Yaar, aaj kuch ajeeb ho gaya. Subah nikal gaya tha chai peene, ek bachcha road par khel raha tha. Jaise hi usne mera haath dekha, woh ruk gaya aur ghoorne laga. Phir uski amma ne bhi dekha aur jhat se usko kheech liya, jaise main koi bhoot hoon. Aisa lagta hai jaise yeh safed daag sirf mera nahi, poore society ka stigma hai. Main try toh kar raha hoon strong rahne ka. Dermatologist ne ek ointment diya hai, lekin dheere kaam karta hai. Ghar waale toh kehte hain "chhota mota hai, kya farak padta hai," par bahar nikalte hi logon ki nigaahein aur sawaal. Koi puchhata hai "yeh kya hai?", koi seedha ignore karta hai. Aap logon se puchhna hai: jab log ghoorte hain, toh aap kya karte ho? Ignore karte ho, jawab dete ho, ya unhe ghoorna seekha dete ho? Koi tareeka hai jo kaam karta hai? Thoda guidance chahiye, kyunki mentally strong rehna mushkil ho raha hai kabhi kabhi.

Hormonal acne ne jawline ka kachra kar diya, shaadi ka proposal reject! 😭 Koi permanent solution?

Haan yaar, aaj toh bahut frustrate ho gayi. Hormonal acne ki wajah se meri jawline literally spotty ho gayi hai. Kal ek rishtedaar aaya tha shaadi ka proposal lekar, aur jaise hi mujhe dekha, woh directly "kya hua face pe?" bol diya. Aise toh confidence ka kachra ho jata hai. Main toh bas apne room mein ghus ke rone lagi. 😭 Iska koi permanent solution hai? Main derma se bhi dikha chuki hoon, woh kehte hain "hormones hain, time lagega". But time toh mera koi nahi hai—log reject kar rahe hain! Currently ek home remedy try kiya hai: neem ka paste + honey. Thoda soothing lagta hai but permanent toh nahi hai. Please koi batado, kya koi specific cream ya tablet hai jo jawline acne ke liye acha kaam kare? Ya phir koi diet change? Koi toh batao yaar, bahut bore ho gayi hoon. 😔

Stress aur Itching ne kiya barbaad! Lichen Planus ka koi natural ilaaj?

Yaar, aaj raat phir neend nahi aayi. Itching itni zyada hai ki skin ka koi hissa bacha nahi. Pata nahi kya ho raha hai. Main sochta tha ki dermatologist ke paas gaya, dawai li, sab theek ho jayega. Lekin nahi. Stress badh raha hai office mein—client ka deadline, boss ka pressure, ghar mein bivi se bhi nahi banti. Aur phir raat ko yeh lichen planus aur bhi zyada active ho jata hai. Ek hafta pehle ek naya cream diya doctor ne, steroid wala. Lagata hoon toh thoda aaram hota hai, lekin phir wapas. Aaj toh soch raha hoon ki kya stress hi trigger hai? Koi bhi tension aati hai, skin pe lal lal patches ubhar aate hain. Aur itching toh raat ko unbearable. Bhai, koi hai yahan jiska same problem ho? Stress ka koi natural remedy bataye? Ya koi aisa khaana hai jo flare-up kam kare? Main toh ab soch raha hoon ki yoga ya meditation try karoon. Lekin pata nahi kaam karega ki nahi. Please koi help karo, bahut pareshan hoon.

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