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amrozin mf 80mg/250mg tablet allopathy (Drotaverine (80mg) + Mefenamic Acid (250mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
amrozin mf 80mg/250mg tablet allopathy (Drotaverine (80mg) + Mefenamic Acid (250mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Mahawat Healthcare Pvt Ltd. Contains Drotaverine (80mg) + Mefenamic Acid (250mg).

Amrozin MF 80mg/250mg Tablet - Uses, Price, Side Effects

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🏭 Mahawat Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is amrozin mf 80mg/250mg tablet used for?

Amrozin MF 80mg/250mg Tablet is a combination of Drotaverine (an antispasmodic) and Mefenamic Acid (an NSAID). It is used to relieve abdominal pain and cramps associated with gastrointestinal spasms, menstrual cramps, and muscle spasms. Drotaverine relaxes smooth muscles, while Mefenamic Acid reduces inflammation and pain.

  • Generic Name: Drotaverine + Mefenamic Acid
  • Manufacturer: Mahawat Healthcare Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 amrozin mf 80mg/250mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

amrozin mf 80mg/250mg tablet का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Drotaverine (80mg) + Mefenamic Acid (250mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Drotaverine + Mefenamic Acid
Brand NameAlmefkem-D Tablet
ManufacturerMahawat Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntispasmodic + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture and light
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributed widely in body tissues
Protein BindingDrotaverine: 95-98%; Mefenamic Acid: 90-98%
MetabolismDrotaverine: Hepatic; Mefenamic Acid: Hepatic (CYP2C9)
Half-LifeDrotaverine: 7-12 hours; Mefenamic Acid: 2-4 hours
ExcretionDrotaverine: Renal and fecal; Mefenamic Acid: Renal (primarily) and fecal
BioavailabilityDrotaverine: ~100%; Mefenamic Acid: ~90%
Onset of ActionDrotaverine: 30-60 min; Mefenamic Acid: 1-2 hours
Peak Plasma TimeDrotaverine: 1-2 hours; Mefenamic Acid: 2-4 hours
Duration of ActionDrotaverine: 4-6 hours; Mefenamic Acid: 6-8 hours

Pharmacodynamics

Mechanism of ActionDrotaverine inhibits phosphodiesterase IV, causing smooth muscle relaxation; Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.
Target ReceptorDrotaverine: PDE4; Mefenamic Acid: COX-1/COX-2
Pharmacodynamic EffectsRelief of smooth muscle spasms and pain; anti-inflammatory effect

📅 When to take amrozin mf 80mg/250mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take amrozin mf 80mg/250mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture and light

⚙️ How amrozin mf 80mg/250mg tablet Works

Drotaverine inhibits phosphodiesterase IV, causing smooth muscle relaxation; Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.

1 Drotaverine inhibits phosphodiesterase IV, increasing cAMP levels in smooth muscle cells.
⬇️
2 Increased cAMP leads to relaxation of smooth muscle via activation of protein kinase A.
⬇️
3 Mefenamic acid inhibits cyclooxygenase (COX-1 and COX-2) enzymes.
⬇️
4 Inhibition of COX reduces conversion of arachidonic acid to prostaglandins.
⬇️
5 Reduced prostaglandins decrease inflammation and pain signaling.
⬇️
6 Combined effects provide antispasmodic and analgesic action.

💊 amrozin mf 80mg/250mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Smooth muscle spasms associated with GI, biliary, or urinary tract disorders; dysmenorrhea

Off-label uses: Renal colic, biliary colic, migraine (limited evidence)

⚠️ What are the side effects of amrozin mf 80mg/250mg tablet?

✅ Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Drowsiness
  • Dry mouth
  • Diarrhea
  • Constipation

🚨 Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Bone marrow suppression

⚠️ Rare Side Effects

  • Pancreatitis
  • Hepatic necrosis
  • Agranulocytosis
  • Thrombocytopenia
  • Aplastic anemia

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for amrozin mf 80mg/250mg tablet

View All

Alternative medicines with exact same composition and strength (Drotaverine (80mg) + Mefenamic Acid (250mg)):

  1. colic dm 80mg/250mg tablet
    Jasmine Healthcare India Pvt Ltd₹5.39💰 92.8% CHEAPER
  2. dimef-dv tablet
    Healsure Lifesciences Pvt. Ltd.₹5.63💰 92.5% CHEAPER
  3. namspas dr tablet
    Psychotropics India Ltd₹15.00💰 80% CHEAPER
  4. drotinam m 80mg/250mg tablet
    Mankind Pharma Ltd₹17.58💰 76.6% CHEAPER
  5. davaindia drotaverine+mefenamic acid 80mg/250mg tablet
    Davaindia Generic Pharmacy₹24.00💰 68% CHEAPER
  6. dotariv m 80mg/250mg tablet
    East African (India) Overseas₹30.00💰 60% CHEAPER
  7. mefen dt 80mg/250mg tablet
    Cureways Remedies₹30.00💰 60% CHEAPER
  8. cytospas 80mg/250mg tablet
    Cytochem Health Care India Pvt Ltd₹33.75💰 55% CHEAPER
  9. drobel-mf tablet
    Blubell Pharma₹33.75💰 55% CHEAPER
  10. dotam mf 80mg/250mg tablet
    Protech Telelinks₹36.56💰 51.3% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels and toxicity

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • ACE inhibitors
  • Diuretics

⚡ Moderate Interactions

  • Anticoagulants
  • Antiplatelets
  • Corticosteroids
  • SSRIs
  • Alcohol

ℹ️ Minor Interactions

  • Antacids
  • Digoxin
  • Phenytoin

🍽️ Food Interactions

Food may delay absorption; avoid high-fat meals.

🍷 Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, asthma, history of NSAID-induced reactions, third trimester pregnancy

📊 Monitoring Parameters

Renal function, hepatic function, CBC, blood pressure, signs of GI bleeding

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; monitor for CNS depression, seizures, renal failure

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

🛑 Myths vs. Facts about amrozin mf 80mg/250mg tablet

  • Myth: Generic substitutes of amrozin mf 80mg/250mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Drotaverine (80mg) + Mefenamic Acid (250mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of amrozin mf 80mg/250mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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