atracade 25mg/ml injection - Uses, Price, Side Effects & Substitutes
What is atracade 25mg/ml injection used for?
Atracurium Besilate Injection (Atracurium besilate) is used to treat Adjunct to general anesthesia for skeletal muscle relaxation; facilitation of endotracheal intubation; mechanical ventilation. It contains Atracurium (25mg/ml), which Competitive antagonist at nicotinic acetylcholine receptors at the neuromuscular. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atracurium besilate
- Manufacturer: Bharat Serums & Vaccines Ltd
- Medicine Form: Allopathy
- Pregnancy Category: C
🇮🇳 atracade 25mg/ml injection के बारे में संक्षिप्त जानकारी (Hindi Summary)
atracade 25mg/ml injection का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Atracurium (25mg/ml) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Atracurium besilate |
|---|---|
| Brand Name | Atracurium Besilate Injection |
| Manufacturer | Bharat Serums & Vaccines Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Peripherally acting |
| Route of Administration | Intravenous (IV) |
| Storage | Refrigerate at 2-8°C; protect from light; do not freeze |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take atracade 25mg/ml injection?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Refrigerate at 2-8°C; protect from light; do not freeze
⚙️ How atracade 25mg/ml injection Works
Competitive antagonist at nicotinic acetylcholine receptors at the neuromuscular junction
💊 atracade 25mg/ml injection Uses in Hindi (Ke Fayde), Benefits & Indications
Adjunct to general anesthesia for skeletal muscle relaxation; facilitation of endotracheal intubation; mechanical ventilation
Off-label uses: Status epilepticus (rarely used)
⚠️ What are the side effects of atracade 25mg/ml injection?
✅ Common Side Effects
- Hypotension
- Flushing
- Bradycardia
- Skin rash
🚨 Serious Side Effects
- Anaphylaxis
- Bronchospasm
- Prolonged neuromuscular blockade
- Respiratory depression
⚠️ Rare Side Effects
- Myopathy
- Histamine release reactions
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | Enhanced neuromuscular blockade |
| Polymyxins | Major | Enhanced neuromuscular blockade |
| Magnesium sulfate | Major | Enhanced neuromuscular blockade |
| Lithium | Major | Enhanced neuromuscular blockade |
| Quinidine | Major | Enhanced neuromuscular blockade |
| Procainamide | Major | Enhanced neuromuscular blockade |
| Inhalational anesthetics | Moderate | Enhanced neuromuscular blockade |
| Succinylcholine | Moderate | Enhanced neuromuscular blockade |
| Calcium channel blockers | Moderate | Enhanced neuromuscular blockade |
| Diuretics | Moderate | Electrolyte imbalance may potentiate blockade |
| Corticosteroids | Minor | Possible prolonged blockade |
| Phenytoin | Minor | Decreased duration of blockade |
| Carbamazepine | Minor | Decreased duration of blockade |
🚨 Major Interactions
- Aminoglycosides
- Polymyxins
- Magnesium sulfate
- Lithium
- Quinidine
- Procainamide
⚡ Moderate Interactions
- Inhalational anesthetics
- Succinylcholine
- Calcium channel blockers
- Diuretics
ℹ️ Minor Interactions
- Corticosteroids
- Phenytoin
- Carbamazepine
🍷 Alcohol Interaction
No specific interaction
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to atracurium or bisbenzylisoquinolinium compounds
📊 Monitoring Parameters
Neuromuscular function (train-of-four monitoring); vital signs; respiratory status
🤱 Lactation Safety
Unknown; use with caution
💊 Overdose Management
Supportive care; neostigmine or other anticholinesterases with atropine to reverse blockade; mechanical ventilation if needed
⏰ Missed Dose
Not applicable (administered by healthcare professional)
🛑 Myths vs. Facts about atracade 25mg/ml injection
- Myth: Generic substitutes of atracade 25mg/ml injection are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Atracurium (25mg/ml)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of atracade 25mg/ml injection can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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