atol l 50mg/50mg tablet allopathy (Atenolol (50mg) + Losartan (50mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
atol l 50mg/50mg tablet allopathy (Atenolol (50mg) + Losartan (50mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by East West Pharma. Contains Atenolol (50mg) + Losartan (50mg).

atol l 50mg/50mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 East West Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is atol l 50mg/50mg tablet used for?

Angizaar AT Tablet (Atenolol + Losartan) is used to treat Hypertension. It contains Atenolol (50mg) + Losartan (50mg), which Atenolol: Selective beta-1 adrenergic receptor blocker reducing heart rate and c. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Atenolol + Losartan
  • Manufacturer: East West Pharma
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 atol l 50mg/50mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

atol l 50mg/50mg tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Atenolol (50mg) + Losartan (50mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Atenolol + Losartan
Brand NameAngizaar AT Tablet
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAntihypertensive (Beta-blocker + ARB)
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAtenolol: Rapidly absorbed from GI tract; Losartan: Well absorbed, undergoes first-pass metabolism.
DistributionAtenolol: Low lipid solubility, minimal CNS penetration; Losartan: High protein binding, distributed widely.
Protein BindingAtenolol: <5%; Losartan: >99%
MetabolismAtenolol: Minimal hepatic metabolism; Losartan: Hepatic via CYP2C9 and CYP3A4 to active metabolite E-3174.
Half-LifeAtenolol: 6-7 hours; Losartan: 2 hours (metabolite 6-9 hours)
ExcretionAtenolol: Renal (unchanged); Losartan: Biliary and renal.
BioavailabilityAtenolol: ~50%; Losartan: ~33%
Onset of ActionAtenolol: 1 hour; Losartan: 1 hour
Peak Plasma TimeAtenolol: 2-4 hours; Losartan: 1 hour (metabolite 3-4 hours)
Duration of ActionAtenolol: 24 hours; Losartan: 24 hours

Pharmacodynamics

Mechanism of ActionAtenolol: Selective beta-1 adrenergic receptor blocker reducing heart rate and contractility; Losartan: Angiotensin II receptor blocker (AT1) causing vasodilation and reduced aldosterone secretion.
Target ReceptorAtenolol: Beta-1 adrenergic receptors; Losartan: AT1 angiotensin II receptors
Pharmacodynamic EffectsReduction in blood pressure, decreased heart rate, reduced cardiac output, inhibition of angiotensin II effects.

💡 How and when to take atol l 50mg/50mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How atol l 50mg/50mg tablet Works

Atenolol: Selective beta-1 adrenergic receptor blocker reducing heart rate and contractility; Losartan: Angiotensin II receptor blocker (AT1) causing vasodilation and reduced aldosterone secretion.

1 Atenolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate and contractility.
⬇️
2 Losartan blocks AT1 receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release.
⬇️
3 Combined effect: decreased peripheral resistance and cardiac output, leading to lower blood pressure.
⬇️
4 Reduced aldosterone decreases sodium and water retention, further lowering blood pressure.

💊 atol l 50mg/50mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Hypertension, chronic stable angina (atenolol), heart failure (losartan), diabetic nephropathy (losartan).

Off-label uses: Migraine prophylaxis (atenolol), Marfan syndrome (atenolol), heart failure with preserved EF (losartan).

⚠️ What are the side effects of atol l 50mg/50mg tablet?

✅ Common Side Effects

  • Fatigue
  • Dizziness
  • Bradycardia
  • Hypotension
  • Hyperkalemia
  • Cough (less with losartan)

🚨 Serious Side Effects

  • Heart block
  • Bronchospasm
  • Angioedema
  • Renal failure
  • Hepatotoxicity

⚠️ Rare Side Effects

  • Peyronie's disease (atenolol)
  • Pancreatitis
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
NSAIDs Major Reduced antihypertensive effect, increased risk of renal impairment
Lithium Major Increased lithium toxicity
Potassium-sparing diuretics Major Hyperkalemia
Digoxin Moderate Bradycardia, heart block
Clonidine Moderate Rebound hypertension on withdrawal
Antacids Minor Reduced absorption of atenolol

🚨 Major Interactions

  • NSAIDs
  • Lithium
  • Potassium-sparing diuretics
  • Other antihypertensives

⚡ Moderate Interactions

  • Digoxin
  • Clonidine
  • CYP2C9 inhibitors (e.g., amiodarone)
  • CYP3A4 inhibitors

ℹ️ Minor Interactions

  • Antacids
  • Cimetidine

🍽️ Food Interactions

Avoid potassium-rich foods; Losartan absorption may be reduced by food.

🍷 Alcohol Interaction

Increased hypotensive effect; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, severe bradycardia, heart block, cardiogenic shock, decompensated heart failure, pregnancy, bilateral renal artery stenosis.

📊 Monitoring Parameters

Blood pressure, heart rate, serum potassium, renal function, ECG.

🤱 Lactation Safety

Atenolol: Excreted in milk, caution; Losartan: Not recommended.

💊 Overdose Management

Supportive care: atropine for bradycardia, vasopressors for hypotension, hemodialysis for atenolol.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip if close to next dose.

🛑 Myths vs. Facts about atol l 50mg/50mg tablet

  • Myth: Generic substitutes of atol l 50mg/50mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Atenolol (50mg) + Losartan (50mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of atol l 50mg/50mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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