ambro 500mg/8mg capsule - Uses, Price, Side Effects & Substitutes
What is ambro 500mg/8mg capsule used for?
Amexine 500mg/8mg capsule (Amoxycillin + Bromhexine) is used to treat ANTI INFECTIVES. It contains Amoxycillin (500mg) + Bromhexine (8mg), which Amoxicillin inhibits bacterial cell wall synthesis; Bromhexine increases respira. Always consult your doctor before use. Take as prescribed.
- Generic Name: Amoxycillin + Bromhexine
- Manufacturer: BIO Ethicals Pharma Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ ambro 500mg/8mg capsule Uses & Benefits
Respiratory tract infections with productive cough; bronchitis, pneumonia.
Off-label uses: Not commonly used off-label.
๐ Drug Information
| Generic Name(s) | Amoxycillin + Bromhexine |
| Brand Name | Amexine 500mg/8mg capsule |
| Manufacturer | BIO Ethicals Pharma Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | ANTI INFECTIVES |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amoxicillin inhibits bacterial cell wall synthesis; Bromhexine increases respiratory tract secretions and reduces mucus viscosity.
Mechanism Steps
๐ก How to Take ambro 500mg/8mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of ambro 500mg/8mg capsule
โ Common Side Effects
- Nausea
- Diarrhea
- Rash
- Dizziness
- Headache
๐จ Serious Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Pseudomembranous colitis
- Seizures
โ ๏ธ Rare Side Effects
- Hepatitis
- Interstitial nephritis
- Agranulocytosis
- Hemolytic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Allopurinol | Major | Increased risk of skin rash |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Probenecid | Moderate | Increased amoxicillin levels |
| Chloramphenicol | Moderate | Antagonistic effect |
| Antacids | Minor | Reduced absorption |
| H2 antagonists | Minor | Reduced absorption |
| Proton pump inhibitors | Minor | Reduced absorption |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
โก Moderate Interactions
- Oral contraceptives
- Probenecid
- Chloramphenicol
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
- Proton pump inhibitors
๐ฝ๏ธ Food Interactions
Food may reduce absorption rate but not extent; avoid acidic fruits/juices.
๐ท Alcohol Interaction
Avoid alcohol; may increase side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins or bromhexine; severe renal impairment.
๐ Monitoring Parameters
Renal function; signs of hypersensitivity; cough improvement.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Gastric lavage; supportive care; hemoperfusion for severe cases.
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double.