alsef 500mg injection - Uses, Price, Side Effects & Substitutes
What is alsef 500mg injection used for?
Accuzon 1g Injection (Ceftriaxone) is used to treat ANTI INFECTIVES. It contains Ceftriaxone (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ceftriaxone
- Manufacturer: Alpa Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ alsef 500mg injection Uses & Benefits
Lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, intra-abdominal infections, meningitis, surgical prophylaxis
Off-label uses: Lyme disease, Syphilis, Gonococcal infections
๐ Drug Information
| Generic Name(s) | Ceftriaxone |
| Brand Name | Accuzon 1g Injection |
| Manufacturer | Alpa Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intramuscular or intravenous |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes
Mechanism Steps
๐ก How to Take alsef 500mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alsef 500mg injection
โ Common Side Effects
- Diarrhea
- Injection site reactions (pain, induration)
- Rash
- Eosinophilia
- Thrombocytosis
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Clostridioides difficile-associated diarrhea
- Hemolytic anemia
- Seizures
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Biliary sludge or pseudolithiasis
- Agranulocytosis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Major | Disulfiram-like reaction |
| Calcium-containing solutions | Major | Precipitation risk, especially in neonates |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Probenecid | Moderate | Decreased ceftriaxone excretion |
| Oral contraceptives | Minor | Reduced contraceptive efficacy |
| BCG vaccine | Minor | Reduced vaccine efficacy |
| Typhoid vaccine | Minor | Reduced vaccine efficacy |
๐จ Major Interactions
- Warfarin
- Alcohol
- Calcium-containing solutions
โก Moderate Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โน๏ธ Minor Interactions
- Oral contraceptives
- BCG vaccine
- Typhoid vaccine
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
Disulfiram-like reaction (flushing, headache, nausea, vomiting) possible
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ceftriaxone or any cephalosporin; hyperbilirubinemic neonates (especially premature); concomitant use with calcium-containing IV solutions in neonates
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection, bleeding tendencies
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding
๐ Overdose Management
Supportive care; hemodialysis may reduce serum levels
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for alsef 500mg injection
View AllAlternative brands with exact same active ingredient (Ceftriaxone (500mg)):
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cadiceft 500mg injectionZydus Healthcare Limited โน15.23 70.7% CHEAPER
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axone 500mg injectionCadila Pharmaceuticals Ltd โน18.28 64.8% CHEAPER
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monogee 500mg injectionZydus Cadila โน18.37 64.7% CHEAPER
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kocef 500mg injectionKopran Ltd โน18.45 64.5% CHEAPER
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Nosocef 500mg InjectionWockhardt Ltd โน21.21 59.2% CHEAPER
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spectacef 500mg injectionSun Pharmaceutical Industries Ltd โน22.50 56.7% CHEAPER
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Spinocef 500mg InjectionAbbott Healthcare Private Limited โน23.00 55.8% CHEAPER
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e cef 500mg injectionLupin Ltd โน24.05 53.8% CHEAPER
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eldocef 500mg injectionElder Pharmaceuticals Ltd โน26.16 49.7% CHEAPER
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Trionix 500mg InjectionSonixa Lifecare โน27.74 46.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.