aconreb 20mg tablet allopathy (Rabeprazole (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aconreb 20mg tablet allopathy (Rabeprazole (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Aconwell Pharma Pvt Ltd. Contains Rabeprazole (20mg).

aconreb 20mg tablet - Uses, Price, Side Effects & Substitutes

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Rabeprazole (20mg) (Click to see all medicines with same salt)
🏭 Aconwell Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aconreb 20mg tablet used for?

Acera 20 Capsule (Rabeprazole) is used to treat Gastroesophageal reflux disease (GERD). It contains Rabeprazole (20mg), which Suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system a. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Rabeprazole
  • Manufacturer: Aconwell Pharma Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aconreb 20mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aconreb 20mg tablet का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Rabeprazole (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Drug Information

Generic Name(s)Rabeprazole
Brand NameAcera 20 Capsule
ManufacturerAconwell Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
Route of AdministrationOral.
StorageStore at 20-25°C (68-77°F); protect from moisture and light.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; peak plasma concentration achieved in 2-4 hours.
DistributionVolume of distribution approximately 0.35 L/kg; extensively distributed into tissues.
Protein BindingApproximately 96% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes.
Half-LifeApproximately 1-2 hours.
ExcretionApproximately 90% excreted in urine as metabolites, remainder in feces.
BioavailabilityApproximately 52% (oral).
Onset of ActionWithin 1 hour.
Peak Plasma Time2-4 hours.
Duration of ActionUp to 24 hours.

Pharmacodynamics

Mechanism of ActionSuppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.
Target ReceptorH+/K+ ATPase (proton pump).
Pharmacodynamic EffectsIncreases intragastric pH, reduces gastric acid secretion, and promotes healing of acid-related lesions.

💡 How and when to take aconreb 20mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from moisture and light.

⚙️ How aconreb 20mg tablet Works

Suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.

1 Rabeprazole is a prodrug that accumulates in the acidic environment of parietal cell canaliculi.
⬇️
2 Protonation converts it to a sulfenamide active form.
⬇️
3 The active form binds covalently to cysteine residues of the H+/K+ ATPase enzyme.
⬇️
4 This inhibits the final step of gastric acid secretion.
⬇️
5 Acid secretion is suppressed until new enzyme molecules are synthesized (24-48 hours).

💊 aconreb 20mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (combination therapy), duodenal ulcer, gastric ulcer.

Off-label uses: Stress ulcer prophylaxis, dyspepsia, prevention of NSAID-induced ulcers.

⚠️ What are the side effects of aconreb 20mg tablet?

✅ Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Constipation
  • Flatulence

🚨 Serious Side Effects

  • Clostridium difficile-associated diarrhea
  • Fractures (hip, wrist, spine) with long-term use
  • Hypomagnesemia
  • Vitamin B12 deficiency
  • Acute interstitial nephritis

⚠️ Rare Side Effects

  • Hepatic encephalopathy
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Atazanavir Major Reduced absorption of atazanavir
Clopidogrel Moderate Reduced clopidogrel efficacy
Methotrexate Major Increased methotrexate toxicity
Digoxin Moderate Increased digoxin absorption
Ketoconazole Moderate Reduced ketoconazole absorption

🚨 Major Interactions

  • Atazanavir
  • Rilpivirine
  • Nelfinavir
  • Methotrexate
  • Cilostazol

⚡ Moderate Interactions

  • Clopidogrel
  • Digoxin
  • Ketoconazole
  • Itraconazole
  • Iron salts
  • Mycophenolate mofetil

ℹ️ Minor Interactions

  • Sucralfate
  • Ampicillin
  • Tetracycline

🍽️ Food Interactions

Food may delay absorption; best taken on an empty stomach.

🍷 Alcohol Interaction

No direct interaction, but alcohol may exacerbate gastric irritation.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to rabeprazole or any component; concomitant use with rilpivirine.

📊 Monitoring Parameters

Symptoms of acid-related disorders; liver function tests (if long-term); magnesium levels (prolonged use).

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Supportive care; no specific antidote; dialysis not effective.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose.

🛑 Myths vs. Facts about aconreb 20mg tablet

  • Myth: Generic substitutes of aconreb 20mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Rabeprazole (20mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aconreb 20mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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