acno gel allopathy (Isotretinoin (0.05% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acno gel allopathy (Isotretinoin (0.05% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Ajanta Pharma Ltd. Contains Isotretinoin (0.05% w/w).

acno gel - Uses, Price, Side Effects & Substitutes

No reviews yet
Isotretinoin (0.05% w/w) (Click to see all medicines with same salt)
🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acno gel used for?

Acutret 10 Capsule (Isotretinoin) is used to treat Severe recalcitrant nodular acne. It contains Isotretinoin (0.05% w/w), which Reduces sebum production, normalizes follicular keratinization, inhibits Propion. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Isotretinoin
  • Manufacturer: Ajanta Pharma Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acno gel के बारे में संक्षिप्त जानकारी (Hindi Summary)

acno gel का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Isotretinoin (0.05% w/w) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

📋 Drug Information

Generic Name(s)Isotretinoin
Brand NameAcutret 10 Capsule
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- First generation
Route of AdministrationOral.
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed orally with high bioavailability; absorption enhanced with food.
DistributionExtensively distributed; crosses placenta; enters breast milk.
Protein Binding99.9% bound to albumin.
MetabolismHepatic metabolism via CYP450 enzymes to active metabolites (4-oxo-isotretinoin).
Half-Life20-24 hours for parent drug; longer for metabolites.
ExcretionExcreted in urine and feces equally.
Bioavailability25% (increased with food).
Onset of Action1-2 weeks for initial improvement.
Peak Plasma Time3-4 hours.
Duration of ActionTherapeutic effect persists weeks after discontinuation.

Pharmacodynamics

Mechanism of ActionReduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.
Target ReceptorRetinoic acid receptors (RARs) and retinoid X receptors (RXRs).
Pharmacodynamic EffectsDecreased sebum excretion, reduced comedogenesis, anti-inflammatory, and antimicrobial.

💡 How and when to take acno gel?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How acno gel Works

Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.

1 Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in the nucleus.
⬇️
2 Modulates gene transcription involved in cell growth, differentiation, and apoptosis.
⬇️
3 Reduces sebocyte proliferation and sebum production.
⬇️
4 Normalizes follicular keratinization, preventing comedone formation.
⬇️
5 Inhibits Propionibacterium acnes growth indirectly by altering sebum composition.
⬇️
6 Exerts anti-inflammatory effects by inhibiting neutrophil chemotaxis and cytokine production.

💊 acno gel Uses in Hindi (Ke Fayde), Benefits & Indications

Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.

Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.

⚠️ What are the side effects of acno gel?

✅ Common Side Effects

  • Cheilitis
  • Dry skin
  • Xerophthalmia
  • Epistaxis
  • Arthralgia
  • Myalgia
  • Headache
  • Increased triglycerides

🚨 Serious Side Effects

  • Pseudotumor cerebri
  • Hepatotoxicity
  • Pancreatitis
  • Depression/suicidal ideation
  • Inflammatory bowel disease
  • Teratogenicity

⚠️ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Vasculitis
  • Hearing impairment
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for acno gel

View All

Alternative brands with exact same active ingredient and strength (Isotretinoin (0.05% w/w)):

  1. isotroin 0.05% gel
    Cipla Ltd₹94.92📈 5.6% COSTLIER
  2. sotret gel
    Sun Pharmaceutical Industries Ltd₹238.00📈 164.8% COSTLIER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Tetracyclines Major Increased risk of pseudotumor cerebri
Vitamin A supplements Major Additive toxicity (hypervitaminosis A)
Methotrexate Major Increased hepatotoxicity risk
Oral contraceptives Major Reduced contraceptive efficacy
Phenytoin Moderate Increased phenytoin levels
Corticosteroids Moderate Increased osteoporosis risk
Azole antifungals Moderate Increased retinoid toxicity
Alcohol Minor Increased hepatotoxicity risk
Antacids Minor Reduced isotretinoin absorption

🚨 Major Interactions

  • Tetracyclines
  • Vitamin A supplements
  • Methotrexate
  • Oral contraceptives (reduced efficacy)

⚡ Moderate Interactions

  • Phenytoin
  • Corticosteroids
  • Antifungals (azole)

ℹ️ Minor Interactions

  • Alcohol
  • Antacids

🍽️ Food Interactions

High-fat meals increase absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.

📊 Monitoring Parameters

Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🛑 Myths vs. Facts about acno gel

  • Myth: Generic substitutes of acno gel are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Isotretinoin (0.05% w/w)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acno gel can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Intermittent fasting se baal jhad rahe? 30 ki umar mein 50 jaisi ho gayi!

Aaj subah jab brush kiya toh haath mein baal ka guchha dekh ke ruk gaya. Seriously, I'm only 30 but lagta hai 50 ki ho gayi hoon. 6 months pehle maine intermittent fasting start kiya tha - 16:8, fir 18:6 bhi try kiya. Weight toh kuch nahi hua but hair fall bohot zyada ho gaya. Pehle toh maine socha stress hai, but phir pata chala ki fasting se nutrition deficiency ho sakti hai. Mummy roz bolti hain, "Beta itna diet karke kya karogi? Baal toh jhad rahe hain." Aur sahi keh rahi hain. Ab maine koi bhi diet nahi kiya, but weight bhi nahi gaya. Metabolism kharab ho chuka hai. Kal hi dermatologist ke paas gaya - vitamins check karwaye. Iron aur Vitamin D kam hai. Koi batao, kya intermittent fasting se hair fall hua hai kisi ko? Aur agar main ab normal khaana shuru kar doon toh kya yeh rukega? Ya fir koi specific supplements loon? Fed up ho gayi hoon apne aap se. Help karo yaar.

Bhai, onion juice se baal aayenge ya sirf ghar ka atmosphere bigdega? 🧅💨

Bc ye onion juice trend dekh ke lagta hai sab log pagal ho gaye hain. Mera dost roz subah pyaz ka juice nikal ke daagta hai head pe, aur ghar mein aisi smell aati hai jaise kitchen mein koi ro raha ho 😂. Uska kehna hai 2 hafte mein results dikhne lage, but honestly I think woh bas apne aap ko convince kar raha hai. Main khud minoxidil try kar raha hoon lekin side effects se darr lagta hai. Onion juice toh natural hai, but kya sach mein kaam karta hai ya bas placebo? Kisi ne try kiya hai? Mera hairline pehle hi retreat ho rahi hai aur friends "takle" bol ke chidhate hain. Ek baar to class mein sab ke saamne "bald spot" ka joke maar diya, gussa aaya but kya kar sakta hoon. Dermatologist ke paas gaya tha toh usne minoxidil suggest kiya, lekin online log bol rahe hai onion juice bhi effective hai. Par honestly, pyaz ki smell 24x7 tolerate karna possible hai? Aur agar koi side effect hua toh? Pls share your experience if you have tried this. Koi genuine advice chahiye, bas bakwas nahi.

Bhai, relatives ka ghar ka nuskha aur acne ka frustration—kya karein? Koi dermatologist-approved product batao pls!

Bhai seriously ab bohot frustration ho raha hai. Kal mausi aayi thi ghar pe, aur bas face dekh ke bolne lagi "Oh beta yeh kya ho gaya? Itne bade pimple! Doodh me haldi aur besan laga kar raat ko laga lo." Like... ma'am I have tried every kitchen remedy since 10th standard. Nothing works. Mera acne cystic hai, dermatologist ne bhi kaha hai ki yeh hormonal hai, but relatives ko toh bas wahi ghar ke nuskhe bataane hain. Or sabse funny part yeh hai ki woh bolegi "Beta filter laga ke photo daalti ho na? Face toh dikhao asli." Hello?? Obviously main filter laga ke daalungi, face pe itne daag hai ki confidence hi nahi aata selfie lene ka. Pimple popping ki aadat bhi hai mujhe, I can't stop. Daag aur badh gaye hain. 🥲 Koi hai jo same situation me ho? Ya koi skincare product suggest karo jo acne ke daag kam kare? Please no home remedies, bas kuch dermatologist-approved batao. 🙏

Browse SaathiMed's Medicines A-Z

Search our extensive medical database alphabetically to find uses, price, composition, and side effects.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install