conflu 150 capsule - Uses, Price, Side Effects & Substitutes
What is conflu 150 capsule used for?
AF 150 Tablet DT (Fluconazole) is used to treat ANTI INFECTIVES. It contains Fluconazole (150mg), which Inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing conversion of lanos. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluconazole
- Manufacturer: East India Pharmaceutical Works Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ conflu 150 capsule Uses & Benefits
Vaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, prophylaxis in immunocompromised patients
Off-label uses: Coccidioidomycosis, histoplasmosis, blastomycosis, dermatophytosis, onychomycosis
๐ Drug Information
| Generic Name(s) | Fluconazole |
| Brand Name | AF 150 Tablet DT |
| Manufacturer | East India Pharmaceutical Works Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis
Mechanism Steps
๐ก How to Take conflu 150 capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of conflu 150 capsule
โ Common Side Effects
- Headache
- Nausea
- Abdominal pain
- Diarrhea
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
- Anaphylaxis
- Exfoliative dermatitis
โ ๏ธ Rare Side Effects
- Alopecia
- Seizures
- Thrombocytopenia
- Leukopenia
- Agranulocytosis
- Hypertriglyceridemia
- Hypokalemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Phenytoin | Major | Increased phenytoin levels, toxicity |
| Sulfonylureas | Major | Hypoglycemia |
| Cisapride | Major | QT prolongation, arrhythmias |
| Terfenadine | Major | QT prolongation, arrhythmias |
| Astemizole | Major | QT prolongation, arrhythmias |
| Rifampin | Major | Decreased fluconazole efficacy |
| Rifabutin | Major | Increased rifabutin levels, uveitis |
| Tacrolimus | Major | Increased tacrolimus levels, nephrotoxicity |
| Sirolimus | Major | Increased sirolimus levels |
| Alfentanil | Major | Increased alfentanil levels, respiratory depression |
| Midazolam | Major | Increased midazolam levels, sedation |
| Triazolam | Major | Increased triazolam levels, sedation |
| Nifedipine | Major | Increased nifedipine levels, hypotension |
| Verapamil | Major | Increased verapamil levels, bradycardia |
| Atorvastatin | Major | Increased statin levels, myopathy |
| Simvastatin | Major | Increased statin levels, myopathy |
| Losartan | Major | Decreased losartan efficacy |
| Methadone | Major | Increased methadone levels, QT prolongation |
| Celecoxib | Major | Increased celecoxib levels |
| Flurbiprofen | Major | Increased flurbiprofen levels |
| Naproxen | Major | Increased naproxen levels |
| Ibuprofen | Major | Increased ibuprofen levels |
| Oral contraceptives | Major | Decreased contraceptive efficacy |
| Pimozide | Major | QT prolongation, arrhythmias |
| Quinidine | Major | QT prolongation, arrhythmias |
| Tolbutamide | Major | Hypoglycemia |
| Zidovudine | Major | Increased zidovudine levels |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Theophylline | Moderate | Increased theophylline levels, toxicity |
| Hydrochlorothiazide | Moderate | Increased fluconazole levels |
| Cimetidine | Minor | Decreased fluconazole absorption |
| Antacids | Minor | Decreased fluconazole absorption |
| Sucralfate | Minor | Decreased fluconazole absorption |
| Didanosine | Minor | Decreased fluconazole absorption |
| Ritonavir | Minor | Increased fluconazole levels |
| Saquinavir | Minor | Increased saquinavir levels |
๐จ Major Interactions
- Warfarin
- Phenytoin
- Sulfonylureas
- Cisapride
- Terfenadine
- Astemizole
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
โก Moderate Interactions
- Cyclosporine
- Theophylline
- Hydrochlorothiazide
- Phenytoin
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
โน๏ธ Minor Interactions
- Cimetidine
- Antacids
- Sucralfate
- Didanosine
- Ritonavir
- Saquinavir
- Zidovudine
๐ฝ๏ธ Food Interactions
No significant food interactions; absorption not affected by food
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to fluconazole or azoles; concomitant use with terfenadine, astemizole, cisapride, pimozide, quinidine
๐ Monitoring Parameters
Liver function tests, renal function, signs of hepatotoxicity, QT interval if risk factors
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Symptomatic and supportive; hemodialysis may enhance elimination
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for conflu 150 capsule
View AllAlternative brands with exact same active ingredient (Fluconazole (150mg)):
-
angloflu 150mg tabletAnglo-French Drugs & Industries Ltd โน4.18 79.3% CHEAPER
-
fluent 150mg tabletTorrent Pharmaceuticals Ltd โน4.62 77.1% CHEAPER
-
markzole 150mg tabletGlenmark Pharmaceuticals Ltd โน4.87 75.9% CHEAPER
-
flucess 150mg tabletNovartis India Ltd โน5.00 75.2% CHEAPER
-
flumed 150mg tabletZydus Healthcare Limited โน5.00 75.2% CHEAPER
-
fluzant 150mg tabletElder Pharmaceuticals Ltd โน5.00 75.2% CHEAPER
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funaz 150mg tabletWockhardt Ltd โน5.00 75.2% CHEAPER
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nucan 150mg tabletMedley Pharmaceuticals โน5.00 75.2% CHEAPER
-
cancap 150 mg tabletInd Swift Laboratories Ltd โน5.19 74.3% CHEAPER
-
davaindia fluconazole 150mg tabletDavaindia Generic Pharmacy โน5.63 72.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.