cheston cold suspension - Cetirizine (2mg/5ml) + Paracetamol (125mg/5ml) medicine

cheston cold suspension - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Cipla Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is cheston cold suspension used for?

Alerid Cold Tablet (Cetirizine + Paracetamol) is used to treat RESPIRATORY. It contains Cetirizine (2mg/5ml) + Paracetamol (125mg/5ml), which Cetirizine: Selective H1 receptor antagonist; Paracetamol: COX inhibition in CNS. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cetirizine + Paracetamol
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š cheston cold suspension Uses & Benefits

Allergic rhinitis, common cold symptoms, fever, mild to moderate pain.

Off-label uses: Urticaria, pruritus (cetirizine); migraine (paracetamol combination).

๐Ÿ“‹ Drug Information

Generic Name(s)Cetirizine + Paracetamol
Brand NameAlerid Cold Tablet
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionCetirizine: Rapidly absorbed; Paracetamol: Rapidly and completely absorbed from GI tract.
DistributionCetirizine: Vd 0.5 L/kg; Paracetamol: Widely distributed, crosses placenta.
Protein BindingCetirizine: 93%; Paracetamol: 10-25%.
MetabolismCetirizine: Minimal hepatic metabolism; Paracetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP450 (minor).
Half-LifeCetirizine: 8.3 hours; Paracetamol: 2-3 hours.
ExcretionCetirizine: Renal (70% unchanged); Paracetamol: Renal (metabolites).
BioavailabilityCetirizine: ~70%; Paracetamol: 68-88%.
Onset of ActionCetirizine: 1 hour; Paracetamol: 30-60 minutes.
Peak Plasma TimeCetirizine: 1 hour; Paracetamol: 30-60 minutes.
Duration of ActionCetirizine: 24 hours; Paracetamol: 4-6 hours.

How It Works

Cetirizine: Selective H1 receptor antagonist; Paracetamol: COX inhibition in CNS, antipyretic via hypothalamic heat-regulating center.

Mechanism Steps

1Cetirizine binds to H1 receptors, blocking histamine action.
2Paracetamol inhibits COX-2 in CNS, reducing prostaglandin synthesis.
3Paracetamol acts on hypothalamic heat-regulating center to lower fever.

๐Ÿ’ก How to Take cheston cold suspension

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cheston cold suspension

โœ… Common Side Effects

  • Drowsiness
  • Fatigue
  • Dry mouth
  • Nausea
  • Headache

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Blood dyscrasias

โš ๏ธ Rare Side Effects

  • Tachycardia
  • Urinary retention
  • Blurred vision
  • Confusion

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Increased hepatotoxicity risk and CNS depression
Warfarin Major Increased INR and bleeding risk
MAOIs Major Increased anticholinergic effects
CNS depressants Major Additive sedation
Isoniazid Major Increased hepatotoxicity risk
Carbamazepine Moderate Decreased paracetamol efficacy
Phenytoin Moderate Decreased paracetamol efficacy
Rifampin Moderate Decreased paracetamol efficacy
Zidovudine Moderate Increased neutropenia risk
Chloramphenicol Minor Increased chloramphenicol half-life
Metoclopramide Minor Increased paracetamol absorption
Probenecid Minor Decreased paracetamol clearance

๐Ÿšจ Major Interactions

  • Alcohol
  • CNS depressants
  • MAOIs
  • Warfarin
  • Isoniazid

โšก Moderate Interactions

  • Barbiturates
  • Carbamazepine
  • Phenytoin
  • Rifampin
  • Zidovudine

โ„น๏ธ Minor Interactions

  • Chloramphenicol
  • Metoclopramide
  • Probenecid

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of paracetamol; grapefruit juice may increase cetirizine levels.

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity with paracetamol; additive CNS depression with cetirizine.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe hepatic impairment, acute liver disease.

๐Ÿ“Š Monitoring Parameters

Liver function tests (if prolonged use or overdose), renal function, CBC.

๐Ÿคฑ Lactation Safety

Cetirizine: Excreted in milk, use caution; Paracetamol: Compatible.

๐Ÿ’Š Overdose Management

Paracetamol overdose: N-acetylcysteine; Cetirizine overdose: supportive care, activated charcoal.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

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