ceflox-cf cream - Uses, Price, Side Effects & Substitutes
What is ceflox-cf cream used for?
Ceflox-CF Cream (Ciprofloxacin + Fluocinolone acetonide) is used to treat DERMA. It contains Ciprofloxacin (0.5% w/w) + Fluocinolone acetonide (0.025% w/w), which Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ciprofloxacin + Fluocinolone acetonide
- Manufacturer: Laborate Pharmaceuticals India Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ ceflox-cf cream Uses & Benefits
Treatment of inflammatory skin conditions with secondary bacterial infection.
Off-label uses: Atopic dermatitis with infection, Seborrheic dermatitis with infection
๐ Drug Information
| Generic Name(s) | Ciprofloxacin + Fluocinolone acetonide |
| Brand Name | Ceflox-CF Cream |
| Manufacturer | Laborate Pharmaceuticals India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Fluoroquinolone antibiotic + Corticosteroid |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC), away from moisture and heat. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Fluocinolone acetonide binds to glucocorticoid receptors, suppressing inflammation.
Mechanism Steps
๐ก How to Take ceflox-cf cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of ceflox-cf cream
โ Common Side Effects
- Skin irritation
- Burning
- Itching
- Dryness
๐จ Serious Side Effects
- Allergic reaction
- Skin atrophy
- Secondary infection
- Adrenal suppression (prolonged use)
โ ๏ธ Rare Side Effects
- Contact dermatitis
- Hypertrichosis
- Hypopigmentation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Theophylline | Major | Increased theophylline levels, risk of toxicity |
| Tizanidine | Major | Increased tizanidine levels, hypotension, sedation |
| NSAIDs | Moderate | Increased CNS stimulation risk |
| Oral antidiabetics | Moderate | Hypoglycemia or hyperglycemia |
| Cyclosporine | Moderate | Increased nephrotoxicity risk |
| Caffeine | Minor | Decreased caffeine clearance |
| Dairy products | Minor | Reduced ciprofloxacin absorption (oral, not topical) |
| Antacids | Minor | Reduced ciprofloxacin absorption (oral, not topical) |
๐จ Major Interactions
- Warfarin
- Theophylline
- Tizanidine
โก Moderate Interactions
- NSAIDs
- Oral antidiabetics
- Cyclosporine
โน๏ธ Minor Interactions
- Caffeine
- Dairy products
- Antacids
๐ฝ๏ธ Food Interactions
No significant food interactions for topical use.
๐ท Alcohol Interaction
No known interaction with topical use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component, viral skin infections, fungal infections, tuberculosis of skin.
๐ Monitoring Parameters
Monitor for skin irritation, signs of systemic absorption, and superinfection.
๐คฑ Lactation Safety
Use with caution; avoid application to breast area.
๐ Overdose Management
Topical overdose unlikely; if excessive application, wash off and treat symptomatically.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.