burnhit cream - Chlorhexidine Gluconate (0.20% w/w) + Silver Sulfadiazine (1% w/w) medicine

Burnhit Cream - Uses, Price, Side Effects, Composition

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๐Ÿญ Care Formulation Labs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is burnhit cream used for?

Burnhit Cream is a combination of Chlorhexidine Gluconate (0.20% w/w) and Silver Sulfadiazine (1% w/w) used to prevent and treat infections in burn wounds. Chlorhexidine is an antiseptic that kills bacteria, while Silver Sulfadiazine stops bacterial growth, promoting healing.

  • Generic Name: Chlorhexidine Gluconate + Silver Sulfadiazine
  • Manufacturer: Care Formulation Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š burnhit cream Uses & Benefits

Prevention and treatment of wound infection in second- and third-degree burns.

Off-label uses: Diabetic foot ulcers, Pressure ulcers, Venous stasis ulcers

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorhexidine Gluconate + Silver Sulfadiazine
Brand NameBurnhit Cream
ManufacturerCare Formulation Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntiseptic and Antimicrobial
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); protect from heat and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption through intact skin; absorption may increase through burned or damaged skin.
DistributionPrimarily local at site of application; limited systemic distribution.
Protein BindingNot well characterized; silver sulfadiazine is highly protein bound (>90%)
MetabolismChlorhexidine is minimally metabolized; silver sulfadiazine is metabolized in the liver.
Half-LifeNot well defined for topical application; systemic half-life of silver sulfadiazine is approximately
ExcretionChlorhexidine is excreted primarily in feces; silver sulfadiazine and its metabolites are excreted in urine.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionRapid; within hours.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionUp to 24 hours with proper application.

How It Works

Chlorhexidine disrupts microbial cell membranes; silver sulfadiazine releases silver ions that bind to microbial DNA and inhibit cell division.

Mechanism Steps

1Chlorhexidine binds to microbial cell membrane phospholipids, increasing permeability and causing leakage of cytoplasmic contents.
2Silver sulfadiazine dissociates to release silver ions, which bind to microbial DNA and inhibit replication.
3Silver ions also bind to sulfhydryl groups in bacterial enzymes, disrupting metabolism.

๐Ÿ’ก How to Take burnhit cream

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of burnhit cream

โœ… Common Side Effects

  • Skin irritation
  • Burning sensation
  • Itching
  • Rash

๐Ÿšจ Serious Side Effects

  • Allergic reactions
  • Stevens-Johnson syndrome
  • Leukopenia
  • Renal toxicity

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Methemoglobinemia
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate Increased risk of bleeding
Corticosteroids Minor May reduce efficacy of silver sulfadiazine

๐Ÿšจ Major Interactions

  • Warfarin
  • Phenytoin
  • Oral hypoglycemics

โšก Moderate Interactions

  • Cimetidine
  • Probenecid
  • Loop diuretics

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to chlorhexidine, silver sulfadiazine, or sulfonamides; pregnancy near term; premature infants.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of infection, allergic reactions, and renal function in extensive burns.

๐Ÿคฑ Lactation Safety

Use with caution; limited data.

๐Ÿ’Š Overdose Management

Overdose unlikely; if systemic toxicity occurs, discontinue use and provide supportive care.

โฐ Missed Dose

Apply as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

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