bucelon 2 tablet - Uses, Price, Side Effects & Substitutes
What is bucelon 2 tablet used for?
Bufatas IV Injection (Busulfan) is used to treat ANTI NEOPLASTICS. It contains Busulfan (2mg), which Alkylating agent that cross-links DNA, inhibiting DNA replication and transcript. Always consult your doctor before use. Take as prescribed.
- Generic Name: Busulfan
- Manufacturer: Celon Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bucelon 2 tablet Uses & Benefits
Conditioning regimen prior to hematopoietic stem cell transplantation; chronic myeloid leukemia.
Off-label uses: Myelodysplastic syndromes, Acute myeloid leukemia
๐ Drug Information
| Generic Name(s) | Busulfan |
| Brand Name | Bufatas IV Injection |
| Manufacturer | Celon Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkylating agent |
| Route of Administration | Intravenous infusion. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Alkylating agent that cross-links DNA, inhibiting DNA replication and transcription.
Mechanism Steps
๐ก How to Take bucelon 2 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bucelon 2 tablet
โ Common Side Effects
- Myelosuppression
- Nausea
- Vomiting
- Mucositis
- Alopecia
๐จ Serious Side Effects
- Veno-occlusive disease
- Pulmonary fibrosis
- Seizures
- Hemorrhagic cystitis
โ ๏ธ Rare Side Effects
- Cardiac tamponade
- Secondary malignancies
- Ovarian failure
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cyclophosphamide | Major | Increased risk of veno-occlusive disease |
| Itraconazole | Major | Increased busulfan exposure |
| Metronidazole | Major | Increased busulfan toxicity |
| Acetaminophen | Major | Reduced busulfan clearance |
| Phenytoin | Moderate | Decreased busulfan levels |
| Warfarin | Moderate | Altered anticoagulation effect |
| Digoxin | Moderate | Decreased digoxin absorption |
| Cimetidine | Minor | Possible increased busulfan levels |
| Ranitidine | Minor | Possible increased busulfan levels |
๐จ Major Interactions
- Cyclophosphamide
- Itraconazole
- Metronidazole
- Acetaminophen
โก Moderate Interactions
- Phenytoin
- Warfarin
- Digoxin
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
๐ฝ๏ธ Food Interactions
No significant food interactions reported.
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to busulfan; pregnancy; severe bone marrow suppression.
๐ Monitoring Parameters
Complete blood count, liver function tests, pulmonary function tests.
๐คฑ Lactation Safety
Contraindicated; busulfan excreted in breast milk.
๐ Overdose Management
Supportive care; hematopoietic growth factors; consider stem cell rescue.
โฐ Missed Dose
Contact healthcare provider immediately; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bucelon 2 tablet
View AllAlternative brands with exact same active ingredient (Busulfan (2mg)):
-
busuphan 2mg tabletElder Pharmaceuticals Ltd โน69.90 26.4% CHEAPER
-
busulmax 2mg tabletGLS Pharma Ltd. โน162.00 70.5% COSTLIER
-
mylefan 2mg tabletCadila Pharmaceuticals Ltd โน249.00 162.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.