Brodine-MS Ointment - Uses, Price, Side Effects
What is brodine-ms ointment used for?
Brodine-MS Ointment is a combination of Metronidazole (1% w/w) and Sucralfate (7% w/w) used for wound healing and infection control. Metronidazole is an antibiotic that fights bacteria, while Sucralfate forms a protective barrier over the wound, promoting healing. It is commonly used for pressure ulcers, diabetic foot ulcers, and venous stasis ulcers.
- Generic Name: Metronidazole + Sucralfate
- Manufacturer: Vhl Pharmaceuticals Private Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ brodine-ms ointment Uses & Benefits
Pressure ulcers, diabetic foot ulcers, infected wounds
Off-label uses: Anal fissures, Hemorrhoids
๐ Drug Information
| Generic Name(s) | Metronidazole + Sucralfate |
| Brand Name | Brodine-MS Ointment |
| Manufacturer | Vhl Pharmaceuticals Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antibiotic + Cytoprotective agent |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Metronidazole: inhibits bacterial DNA synthesis; Sucralfate: forms protective barrier over ulcer
Mechanism Steps
๐ก How to Take brodine-ms ointment
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of brodine-ms ointment
โ Common Side Effects
- Skin irritation
- Burning
- Itching
๐จ Serious Side Effects
- Allergic reaction
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Metallic taste
- Nausea (if absorbed)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Moderate | Disulfiram-like reaction |
| Disulfiram | Major | Psychotic reactions |
๐จ Major Interactions
- Disulfiram
- Warfarin
- Lithium
โก Moderate Interactions
- Phenytoin
- Phenobarbital
- Cimetidine
โน๏ธ Minor Interactions
- Alcohol
- Oral contraceptives
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
Avoid alcohol; may cause disulfiram-like reaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to metronidazole or sucralfate
๐ Monitoring Parameters
Wound healing, signs of infection, skin irritation
๐คฑ Lactation Safety
Use with caution; metronidazole excreted in milk
๐ Overdose Management
Unlikely with topical use; if ingested, symptomatic treatment
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose