broclars 250mg tablet - Clarithromycin (250mg) medicine

broclars 250mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Shreeyam Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is broclars 250mg tablet used for?

Acnesol CL Gel (Clarithromycin) is used to treat ANTI INFECTIVES. It contains Clarithromycin (250mg), which Binds to 50S ribosomal subunit of bacteria, inhibiting protein synthesis.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clarithromycin
  • Manufacturer: Shreeyam Healthcare
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š broclars 250mg tablet Uses & Benefits

Acne vulgaris

Off-label uses: Bacterial skin infections, Rosacea

๐Ÿ“‹ Drug Information

Generic Name(s)Clarithromycin
Brand NameAcnesol CL Gel
ManufacturerShreeyam Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption is low when applied to intact skin.
DistributionNot well characterized for topical use; systemic distribution follows oral administration.
Protein BindingApproximately 70% bound to plasma proteins.
MetabolismMetabolized in the liver via CYP3A4 isoenzyme to active metabolite 14-hydroxyclarithromycin.
Half-Life3-4 hours for parent drug; 5-6 hours for active metabolite.
ExcretionPrimarily excreted in urine (20-30% as unchanged drug) and feces.
BioavailabilityNot applicable for topical formulation; oral bioavailability is ~50%.
Onset of ActionWithin a few days of topical application.
Peak Plasma TimeNot applicable for topical use; oral peak at 2-3 hours.
Duration of ActionNot well defined for topical use; typically applied twice daily.

How It Works

Binds to 50S ribosomal subunit of bacteria, inhibiting protein synthesis.

Mechanism Steps

1Clarithromycin binds to the 50S ribosomal subunit of susceptible bacteria.
2Inhibits translocation of peptidyl-tRNA.
3Blocks protein synthesis, leading to bacteriostatic effect.

๐Ÿ’ก How to Take broclars 250mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of broclars 250mg tablet

โœ… Common Side Effects

  • Skin irritation
  • Dryness
  • Peeling
  • Redness

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Pseudomembranous colitis
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cisapride Major Increased risk of cardiac arrhythmias
Pimozide Major Increased risk of QT prolongation
Ergotamine Major Increased risk of ergotism
Lovastatin Major Increased risk of rhabdomyolysis
Simvastatin Major Increased risk of rhabdomyolysis
Warfarin Moderate Increased INR and bleeding risk
Theophylline Moderate Increased theophylline levels
Carbamazepine Moderate Increased carbamazepine levels
Digoxin Moderate Increased digoxin levels
Oral contraceptives Moderate Reduced contraceptive efficacy
Zidovudine Minor Decreased zidovudine levels
Phenytoin Minor Altered phenytoin levels
Valproate Minor Decreased valproate levels

๐Ÿšจ Major Interactions

  • Cisapride
  • Pimozide
  • Ergotamine
  • Lovastatin
  • Simvastatin

โšก Moderate Interactions

  • Warfarin
  • Theophylline
  • Carbamazepine
  • Digoxin
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Zidovudine
  • Phenytoin
  • Valproate

๐Ÿฝ๏ธ Food Interactions

No significant food interactions for topical use.

๐Ÿท Alcohol Interaction

No known interaction with topical use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clarithromycin or macrolides; concurrent use with cisapride, pimozide, ergotamine.

๐Ÿ“Š Monitoring Parameters

Clinical response; skin irritation.

๐Ÿคฑ Lactation Safety

Use with caution; excreted in breast milk.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for broclars 250mg tablet

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Alternative brands with exact same active ingredient (Clarithromycin (250mg)):

Medical Note: Always consult your doctor before switching medications.

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