biguard 50mg tablet - Uses, Price, Side Effects & Substitutes
What is biguard 50mg tablet used for?
Adiflam 50mg Tablet (Diclofenac) is used to treat PAIN ANALGESICS. It contains Diclofenac (50mg), which Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthe. Always consult your doctor before use. Take as prescribed.
- Generic Name: Diclofenac
- Manufacturer: Berry & Herbs Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ biguard 50mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Diclofenac |
| Brand Name | Adiflam 50mg Tablet |
| Manufacturer | Berry & Herbs Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take biguard 50mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biguard 50mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Dyspepsia
- Abdominal pain
- Flatulence
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Perforation
- Renal failure
- Hepatic failure
- Myocardial infarction
- Stroke
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Aseptic meningitis
- Hematologic disorders (agranulocytosis, aplastic anemia)
- Hepatitis
- Nephrotic syndrome
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium levels and toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Aspirin | Major | Increased risk of gastrointestinal ulcers and bleeding |
| Other NSAIDs | Major | Additive gastrointestinal and renal toxicity |
| Anticoagulants | Major | Increased bleeding risk |
| Corticosteroids | Major | Increased risk of gastrointestinal ulcers |
| ACE inhibitors | Moderate | Reduced antihypertensive effect and increased renal impairment risk |
| Diuretics | Moderate | Reduced diuretic effect and increased renal impairment risk |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Tacrolimus | Moderate | Increased nephrotoxicity |
| Quinolone antibiotics | Moderate | Increased risk of seizures |
| Antacids | Minor | Reduced absorption of diclofenac |
| Cholestyramine | Minor | Reduced absorption of diclofenac |
| Digoxin | Minor | Increased digoxin levels |
| Phenytoin | Minor | Increased phenytoin levels |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Aspirin
- Other NSAIDs
- Anticoagulants
- Corticosteroids
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Cyclosporine
- Tacrolimus
- Quinolone antibiotics
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Digoxin
- Phenytoin
๐ฝ๏ธ Food Interactions
Food may delay absorption but does not significantly affect overall bioavailability.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding and ulcers.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to diclofenac or any NSAID; history of asthma, urticaria, or allergic-type reactions after aspirin/NSAIDs; active peptic ulcer or GI bleeding; severe heart failure; severe renal or hepatic impairment; perioperative pain in CABG surgery.
๐ Monitoring Parameters
Renal function, liver function, blood pressure, signs of GI bleeding, CBC.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for biguard 50mg tablet
View AllAlternative brands with exact same active ingredient (Diclofenac (50mg)):
-
adiflam 50mg injectionLeben Life Sciences Pvt Ltd โน4.17 91.7% CHEAPER
-
zonac 50mg injectionZee Laboratories โน4.50 91% CHEAPER
-
cannact 50mg tabletAstra IDL MAX โน4.78 90.4% CHEAPER
-
fin 50mg tabletAan Pharma Pvt Ltd โน5.00 90% CHEAPER
-
ultramark 1 tabletTerrace Pharmaceuticals โน5.00 90% CHEAPER
-
divorel 50mg tabletMedisys Biotech Pvt Ltd โน6.00 88% CHEAPER
-
runac 50mg tabletSun Pharmaceutical Industries Ltd โน6.00 88% CHEAPER
-
Tromagesic 50mg TabletThemis Medicare Ltd โน6.00 88% CHEAPER
-
diclofam 50mg tabletMax Life Science โน6.07 87.9% CHEAPER
-
haloran 50mg tabletHindustan Antibiotics Ltd โน6.10 87.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.