bfenac sp 100mg/325mg/15mg tablet - Uses, Price, Side Effects & Substitutes
What is bfenac sp 100mg/325mg/15mg tablet used for?
At Sp Tablet (Diclofenac + Paracetamol) is used to treat PAIN ANALGESICS. It contains Diclofenac (100mg) + Paracetamol (325mg), which Diclofenac: Inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin sy. Always consult your doctor before use. Take as prescribed.
- Generic Name: Diclofenac + Paracetamol
- Manufacturer: S.Bee Life Sciences
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bfenac sp 100mg/325mg/15mg tablet Uses & Benefits
Management of mild to moderate pain, fever, and inflammation (e.g., headache, dental pain, menstrual cramps, musculoskeletal pain).
Off-label uses: Diclofenac: Topical for actinic keratosis; Paracetamol: None commonly.
๐ Drug Information
| Generic Name(s) | Diclofenac + Paracetamol |
| Brand Name | At Sp Tablet |
| Manufacturer | S.Bee Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Diclofenac: Inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis; Paracetamol: Central COX inhibition and activation of descending serotonergic pathways.
Mechanism Steps
๐ก How to Take bfenac sp 100mg/325mg/15mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bfenac sp 100mg/325mg/15mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Abdominal pain
- Diarrhea
- Constipation
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Renal failure
- Cardiovascular thrombotic events
- Stevens-Johnson syndrome
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Pancreatitis
- Hematologic disorders (agranulocytosis, thrombocytopenia)
- Interstitial nephritis
- Hepatic necrosis
- Aseptic meningitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Diuretics | Major | Reduced diuretic effect, increased nephrotoxicity |
| Aspirin | Major | Increased GI bleeding risk |
| Other NSAIDs | Major | Additive GI and renal toxicity |
| Anticoagulants | Major | Increased bleeding risk |
| Corticosteroids | Moderate | Increased GI ulceration risk |
| SSRIs | Moderate | Increased bleeding risk |
| Alcohol | Moderate | Increased hepatotoxicity and GI bleeding |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Tacrolimus | Moderate | Increased nephrotoxicity |
| Quinolone antibiotics | Moderate | Increased CNS side effects |
| Antacids | Minor | Reduced absorption of diclofenac |
| Cholestyramine | Minor | Reduced absorption of diclofenac |
| Digoxin | Minor | Increased digoxin levels |
| Phenytoin | Minor | Increased phenytoin levels |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- ACE inhibitors
- Diuretics
- Aspirin
- Other NSAIDs
- Anticoagulants
โก Moderate Interactions
- Corticosteroids
- SSRIs
- Alcohol
- Cyclosporine
- Tacrolimus
- Quinolone antibiotics
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Digoxin
- Phenytoin
๐ฝ๏ธ Food Interactions
Food may delay absorption of diclofenac; paracetamol absorption unaffected.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity with chronic alcohol use (paracetamol) and GI bleeding (diclofenac).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to diclofenac, paracetamol, or any component; Active peptic ulcer; History of GI bleeding; Severe hepatic or renal impairment; Third trimester of pregnancy; Asthma with NSAID sensitivity; Coronary artery bypass graft surgery.
๐ Monitoring Parameters
Liver function tests, renal function, blood pressure, signs of GI bleeding, CBC (if prolonged use).
๐คฑ Lactation Safety
Diclofenac: Excreted in breast milk in low amounts, generally considered safe; Paracetamol: Excreted in breast milk in low amounts, considered safe.
๐ Overdose Management
Paracetamol overdose: Administer N-acetylcysteine; Diclofenac overdose: Supportive care, activated charcoal if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near time of next dose; do not double dose.