bestor 10 tablet - Uses, Price, Side Effects & Substitutes
What is bestor 10 tablet used for?
Arvast 10 Tablet (Rosuvastatin) is used to treat CARDIAC. It contains Rosuvastatin (10mg), which Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in choleste. Always consult your doctor before use. Take as prescribed.
- Generic Name: Rosuvastatin
- Manufacturer: Biocon
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bestor 10 tablet Uses & Benefits
Hypercholesterolemia (primary and mixed dyslipidemia), homozygous familial hypercholesterolemia, prevention of cardiovascular events in patients with risk factors.
Off-label uses: Chronic kidney disease, non-alcoholic fatty liver disease, post-transplant hyperlipidemia.
๐ Drug Information
| Generic Name(s) | Rosuvastatin |
| Brand Name | Arvast 10 Tablet |
| Manufacturer | Biocon |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG CoA inhibitors (statins) |
| Route of Administration | Oral. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, leading to reduced intracellular cholesterol levels and increased LDL receptor expression.
Mechanism Steps
๐ก How to Take bestor 10 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bestor 10 tablet
โ Common Side Effects
- Myalgia
- Headache
- Nausea
- Diarrhea
- Constipation
- Abdominal pain
- Asthenia
๐จ Serious Side Effects
- Rhabdomyolysis
- Myopathy
- Hepatotoxicity
- Acute renal failure (secondary to rhabdomyolysis)
- Hypersensitivity reactions
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Memory loss
- Gynecomastia
- Interstitial lung disease
- Tendon rupture
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cyclosporine | Major | Increased rosuvastatin plasma concentration; risk of myopathy/rhabdomyolysis. |
| Gemfibrozil | Major | Increased risk of myopathy/rhabdomyolysis. |
| Warfarin | Major | Increased INR and bleeding risk. |
| Fibrates | Major | Increased risk of myopathy. |
| Niacin (lipid-lowering doses) | Major | Increased risk of myopathy/rhabdomyolysis. |
| Erythromycin | Moderate | Moderate increase in rosuvastatin levels. |
| Itraconazole | Moderate | Moderate increase in rosuvastatin levels. |
| Ketoconazole | Moderate | Moderate increase in rosuvastatin levels. |
| Protease inhibitors | Moderate | Increased rosuvastatin exposure. |
| Amiodarone | Moderate | Possible increased risk of myopathy. |
| Verapamil | Moderate | Possible increased rosuvastatin levels. |
| Digoxin | Minor | No significant interaction; minor increase in digoxin levels. |
| Oral contraceptives | Minor | Minor increase in ethinyl estradiol and norgestrel levels. |
| Antacids (aluminum/magnesium) | Minor | Reduced rosuvastatin absorption; separate by 2 hours. |
| Fenofibrate | Minor | No significant interaction. |
๐จ Major Interactions
- Cyclosporine
- Gemfibrozil
- Warfarin
- Fibrates
- Niacin (lipid-lowering doses)
โก Moderate Interactions
- Erythromycin
- Itraconazole
- Ketoconazole
- Protease inhibitors
- Amiodarone
- Verapamil
โน๏ธ Minor Interactions
- Digoxin
- Oral contraceptives
- Antacids (aluminum/magnesium)
- Fenofibrate
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase rosuvastatin exposure; avoid large quantities. Food does not affect absorption.
๐ท Alcohol Interaction
Alcohol may increase risk of hepatotoxicity; limit consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to rosuvastatin.
๐ Monitoring Parameters
Lipid profile, liver function tests (ALT, AST) at baseline and periodically, creatine kinase if muscle symptoms occur.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk in animal studies.
๐ Overdose Management
No specific antidote; symptomatic and supportive care; monitor liver function and CK levels.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bestor 10 tablet
View AllAlternative brands with exact same active ingredient (Rosuvastatin (10mg)):
-
rosze 10mg tabletZeelab Pharmacy Pvt Ltd โน15.00 89.9% CHEAPER
-
davaindia rosuvastatin 10mg tabletDavaindia Generic Pharmacy โน21.00 85.9% CHEAPER
-
danavish rosuvastatin 10mg tabletDanavish Healthcare โน23.00 84.6% CHEAPER
-
Rvsat 10 TabletDR Best pharmaceuticals Pvt Ltd โน25.00 83.2% CHEAPER
-
acmerose 10mg tabletCitric Labs โน28.13 81.1% CHEAPER
-
acmerose 10 tabletAcmedix Pharma LLP โน30.00 79.9% CHEAPER
-
fortius 10 tabletAbbott โน30.00 79.9% CHEAPER
-
ab-rozu 10 tabletAbbott โน34.03 77.2% CHEAPER
-
rosuson 10 tabletUnison Pharmaceuticals Pvt Ltd โน36.80 75.3% CHEAPER
-
Rosuone 10mg TabletMission Cure Pharma Pvt Ltd โน40.00 73.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.