benther as 60mg injection - Arteether (60mg) medicine

Benther AS 60mg Injection - Uses, Price, Side Effects

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๐Ÿญ Bennet Pharmaceuticals Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is benther as 60mg injection used for?

Benther AS 60mg Injection contains Arteether, an antimalarial medication used to treat severe malaria caused by Plasmodium falciparum. It works by interfering with the parasite's ability to replicate, effectively clearing the infection. This injection is typically administered in a hospital setting under medical supervision.

  • Generic Name: Arteether
  • Manufacturer: Bennet Pharmaceuticals Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š benther as 60mg injection Uses & Benefits

Treatment of uncomplicated and severe falciparum malaria; chloroquine-resistant malaria.

Off-label uses: Babesiosis (limited evidence); autoimmune diseases (not recommended).

๐Ÿ“‹ Drug Information

Generic Name(s)Arteether
Brand NameArtisun 150mg Injection
ManufacturerBennet Pharmaceuticals Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationIntramuscular injection only.
StorageStore at 20-25ยฐC; protect from light; do not freeze.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak plasma concentrations achieved within 2-3 hours.
DistributionWidely distributed in body tissues; crosses blood-brain barrier.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismMetabolized in the liver primarily by CYP2A6 to dihydroartemisinin (active metabolite).
Half-LifeApproximately 23 hours for arteether; 4-11 hours for dihydroartemisinin.
ExcretionPrimarily excreted in urine (up to 80%) and feces.
BioavailabilityNot applicable (parenteral administration); high systemic availability.
Onset of ActionRapid onset; clinical improvement within 24-48 hours.
Peak Plasma Time2-3 hours after intramuscular injection.
Duration of ActionLong-acting; single dose provides therapeutic levels for several days.

How It Works

Arteether is converted to dihydroartemisinin, which generates free radicals that damage parasite proteins and membranes.

Mechanism Steps

1Arteether is hydrolyzed to dihydroartemisinin (DHA) in the liver.
2DHA interacts with heme (from hemoglobin digestion) in the parasite.
3Formation of free radicals (carbon-centered radicals) via cleavage of endoperoxide bridge.

๐Ÿ’ก How to Take benther as 60mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of benther as 60mg injection

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Abdominal pain
  • Injection site pain

๐Ÿšจ Serious Side Effects

  • QTc prolongation
  • Severe hemolysis (in G6PD deficiency)
  • Hepatotoxicity
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Neurotoxicity (ataxia, tremors)
  • Hemolytic anemia
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Mefloquine Moderate Increased risk of QT prolongation
Halofantrine Major Increased risk of cardiotoxicity

๐Ÿšจ Major Interactions

  • Mefloquine
  • Quinine
  • Halofantrine

โšก Moderate Interactions

  • CYP2A6 inhibitors (e.g., ketoconazole)
  • CYP2A6 inducers (e.g., rifampin)

โ„น๏ธ Minor Interactions

  • Anticoagulants (e.g., warfarin)
  • Antiepileptics (e.g., carbamazepine)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to arteether or artemisinin derivatives; severe hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Parasite count, hemoglobin, liver function tests, ECG if co-administered with cardiotoxic drugs.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised; discontinue breastfeeding or drug.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; no specific antidote; monitor ECG and liver function.

โฐ Missed Dose

Administer as soon as remembered; do not double dose; maintain dosing interval.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for benther as 60mg injection

View All

Alternative brands with exact same active ingredient (Arteether (60mg)):

Medical Note: Always consult your doctor before switching medications.

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