Benther AL DS Tablet - Uses, Price, Side Effects
What is benther al ds tablet used for?
Benther AL DS Tablet is an antimalarial medicine used to treat uncomplicated malaria caused by Plasmodium falciparum. It contains Artemether (80mg) and Lumefantrine (480mg). Artemether rapidly reduces the parasite count, while Lumefantrine eliminates remaining parasites, preventing relapse. It is taken twice daily for 3 days.
- Generic Name: Artemether + Lumefantrine
- Manufacturer: Bennet Pharmaceuticals Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ benther al ds tablet Uses & Benefits
Uncomplicated falciparum malaria, chloroquine-resistant malaria.
Off-label uses: Severe malaria (IV artemether not available), babesiosis.
๐ Drug Information
| Generic Name(s) | Artemether + Lumefantrine |
| Brand Name | Artether L |
| Manufacturer | Bennet Pharmaceuticals Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI MALARIALS |
| Action Class | Antimalarial |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Artemether: Produces free radicals damaging parasite membranes; Lumefantrine: Inhibits heme polymerization.
Mechanism Steps
๐ก How to Take benther al ds tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of benther al ds tablet
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
๐จ Serious Side Effects
- QT prolongation
- Cardiac arrhythmias
- Severe allergic reactions
- Hemolytic anemia (G6PD deficiency)
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Nephrotoxicity
- Neurotoxicity (high doses)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Moderate | Increased artemether levels |
| Rifampin | Major | Decreased lumefantrine efficacy |
๐จ Major Interactions
- CYP3A4 inducers (rifampin, carbamazepine)
- CYP3A4 inhibitors (ketoconazole, ritonavir)
- Antiarrhythmics (amiodarone, quinidine)
โก Moderate Interactions
- Oral contraceptives
- Antipsychotics
- Macrolide antibiotics
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
๐ฝ๏ธ Food Interactions
Enhanced absorption with fatty foods; avoid grapefruit juice.
๐ท Alcohol Interaction
No significant interaction reported.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, known QT prolongation, concomitant with CYP3A4 inducers.
๐ Monitoring Parameters
ECG (QT interval), parasitemia, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Symptomatic and supportive; monitor ECG for QT prolongation.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip and resume schedule.