azytic-sf combikit - Uses, Price, Side Effects & Substitutes
What is azytic-sf combikit used for?
Azithral XP 150mg/1000mg/1000mg Tablet (Fluconazole + Azithromycin) is used to treat Treatment of vaginal candidiasis with concurrent bacterial vaginosis or cervicitis; mixed gynecological infections.. It contains Fluconazole (150mg) + Azithromycin (1000mg), which Fluconazole inhibits fungal cytochrome P450 14α-demethylase, preventing ergoste. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluconazole + Azithromycin
- Manufacturer: Numera Life Sciences
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 azytic-sf combikit के बारे में संक्षिप्त जानकारी (Hindi Summary)
azytic-sf combikit का उपयोग मुख्य रूप से gynaecological और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Fluconazole (150mg) + Azithromycin (1000mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Fluconazole + Azithromycin |
|---|---|
| Brand Name | Azithral XP 150mg/1000mg/1000mg Tablet |
| Manufacturer | Numera Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Antifungal + Antibiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take azytic-sf combikit?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture.
⚙️ How azytic-sf combikit Works
Fluconazole inhibits fungal cytochrome P450 14α-demethylase, preventing ergosterol synthesis; Azithromycin binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.
💊 azytic-sf combikit Uses in Hindi (Ke Fayde), Benefits & Indications
Treatment of vaginal candidiasis with concurrent bacterial vaginosis or cervicitis; mixed gynecological infections.
Off-label uses: Treatment of pelvic inflammatory disease (PID) when fungal co-infection suspected.
⚠️ What are the side effects of azytic-sf combikit?
✅ Common Side Effects
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Vaginal discharge
🚨 Serious Side Effects
- QT prolongation
- Torsades de pointes
- Hepatotoxicity
- Stevens-Johnson syndrome
- Anaphylaxis
⚠️ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Pancreatitis
- Hearing loss
- Tinnitus
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Cisapride | Major | Risk of cardiac arrhythmias |
| Terfenadine | Major | Risk of QT prolongation |
| Astemizole | Major | Risk of QT prolongation |
| Pimozide | Major | Risk of cardiac toxicity |
| Quinidine | Major | Risk of QT prolongation |
| Ergotamine | Major | Risk of ergotism |
| Oral hypoglycemics | Moderate | Increased hypoglycemic effect |
| Phenytoin | Moderate | Increased phenytoin levels |
| Rifampin | Moderate | Decreased fluconazole levels |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Theophylline | Moderate | Increased theophylline levels |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Minor | Possible reduced efficacy |
| Antacids | Minor | Reduced azithromycin absorption |
| H2 antagonists | Minor | Reduced azithromycin absorption |
🚨 Major Interactions
- Warfarin
- Cisapride
- Terfenadine
- Astemizole
- Pimozide
- Quinidine
- Ergotamine
⚡ Moderate Interactions
- Oral hypoglycemics
- Phenytoin
- Rifampin
- Cyclosporine
- Theophylline
- Digoxin
ℹ️ Minor Interactions
- Oral contraceptives
- Antacids
- H2 antagonists
🍽️ Food Interactions
Azithromycin absorption may be reduced with food; fluconazole unaffected.
🍷 Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to azithromycin, fluconazole, or other azoles; concurrent use with cisapride, terfenadine, astemizole, pimozide, quinidine, ergotamine.
📊 Monitoring Parameters
Liver function tests, renal function, ECG (if risk factors), signs of superinfection.
🤱 Lactation Safety
Fluconazole and azithromycin are excreted in breast milk; use with caution.
💊 Overdose Management
Supportive care; gastric lavage if recent; monitor ECG for QT prolongation; hemodialysis may remove fluconazole.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
🛑 Myths vs. Facts about azytic-sf combikit
- Myth: Generic substitutes of azytic-sf combikit are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Fluconazole (150mg) + Azithromycin (1000mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of azytic-sf combikit can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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