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azvin 500mg injection allopathy (Aztreonam (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
azvin 500mg injection allopathy (Aztreonam (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Arvincare Pharma. Contains Aztreonam (500mg).

Azvin 500mg Injection - Uses, Price, Side Effects

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Aztreonam (500mg) (Click to see all medicines with same salt)
🏭 Arvincare Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is azvin 500mg injection used for?

Azvin 500mg Injection contains Aztreonam, a monobactam antibiotic used to treat moderate to severe bacterial infections caused by susceptible gram-negative bacteria, including urinary tract, respiratory, intra-abdominal, and skin infections. It works by inhibiting bacterial cell wall synthesis.

  • Generic Name: Aztreonam
  • Manufacturer: Arvincare Pharma
  • Medicine Form: Allopathy
  • Pregnancy Category: B

🇮🇳 azvin 500mg injection के बारे में संक्षिप्त जानकारी (Hindi Summary)

azvin 500mg injection का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aztreonam (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

📋 Drug Information

Generic Name(s)Aztreonam
Brand NameAzenam 1gm Injection
ManufacturerArvincare Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMonobactams
Route of AdministrationIntravenous (IV) or intramuscular (IM) injection.
StorageStore at 20-25°C (68-77°F); protect from light; reconstituted solutions stable for 48 hours at room temperature or 7 days under refrigeration.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration results in rapid and complete absorption; intravenous administration provides immediate systemic availability.
DistributionWidely distributed into body tissues and fluids including cerebrospinal fluid (with inflamed meninges), bile, sputum, and pleural fluid.
Protein BindingApproximately 56% bound to plasma proteins.
MetabolismMetabolized primarily by hydrolysis of the beta-lactam ring to inactive metabolites.
Half-LifeApproximately 1.7 hours in patients with normal renal function; prolonged in renal impairment.
ExcretionPrimarily excreted unchanged in urine (60-70%) via glomerular filtration and tubular secretion; small amount in feces.
Bioavailability100% (intravenous); approximately 100% (intramuscular).
Onset of ActionRapid; within 30 minutes after intravenous administration.
Peak Plasma TimeIntravenous: immediately after infusion; intramuscular: 1 hour.
Duration of ActionApproximately 6-8 hours depending on renal function.

Pharmacodynamics

Mechanism of ActionInhibits bacterial cell wall synthesis by binding to penicillin-binding protein 3 (PBP3), leading to cell lysis and death.
Target ReceptorPenicillin-binding protein 3 (PBP3) in Gram-negative bacteria.
Pharmacodynamic EffectsBactericidal activity against aerobic Gram-negative bacteria; no activity against Gram-positive or anaerobic bacteria.

📅 When to take azvin 500mg injection?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take azvin 500mg injection?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light; reconstituted solutions stable for 48 hours at room temperature or 7 days under refrigeration.

⚙️ How azvin 500mg injection Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding protein 3 (PBP3), leading to cell lysis and death.

1 Aztreonam binds to penicillin-binding protein 3 (PBP3) on the inner membrane of Gram-negative bacteria.
⬇️
2 Inhibition of PBP3 prevents transpeptidation, a key step in peptidoglycan cross-linking.
⬇️
3 Disruption of cell wall synthesis leads to osmotic instability and bacterial cell lysis.
⬇️
4 Bactericidal effect is achieved due to autolytic enzyme activation.

💊 azvin 500mg injection Uses in Hindi (Ke Fayde), Benefits & Indications

Treatment of infections caused by susceptible Gram-negative bacteria including urinary tract infections, lower respiratory tract infections, septicemia, skin and skin structure infections, intra-abdominal infections, and gynecologic infections.

Off-label uses: Febrile neutropenia (in combination), Meningitis (with inflamed meninges)

⚠️ What are the side effects of azvin 500mg injection?

✅ Common Side Effects

  • Injection site reactions (pain, phlebitis)
  • Diarrhea
  • Nausea
  • Vomiting
  • Rash

🚨 Serious Side Effects

  • Severe hypersensitivity reactions (anaphylaxis)
  • Clostridioides difficile-associated diarrhea
  • Seizures
  • Hepatotoxicity

⚠️ Rare Side Effects

  • Pseudomembranous colitis
  • Blood dyscrasias (neutropenia, thrombocytopenia)
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Moderate Increased bleeding risk
Probenecid Moderate Decreased renal excretion of aztreonam
Aminoglycosides Moderate Additive nephrotoxicity

🚨 Major Interactions

  • Warfarin
  • Live Typhoid Vaccine
  • BCG Vaccine

⚡ Moderate Interactions

  • Probenecid
  • Aminoglycosides
  • Furosemide

ℹ️ Minor Interactions

  • Chloramphenicol
  • Tetracyclines

🍽️ Food Interactions

No significant food interactions; injection only.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver
Low
Kidney
Moderate
Heart
Low
Pregnancy
Category B

🚫 Contraindications

Hypersensitivity to aztreonam or any component of the formulation.

📊 Monitoring Parameters

Renal function (especially in elderly or with concurrent nephrotoxic drugs), liver function tests, signs of hypersensitivity, and superinfection.

🤱 Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Administer as soon as possible; if near next dose, skip missed dose and resume regular schedule.

🛑 Myths vs. Facts about azvin 500mg injection

  • Myth: Generic substitutes of azvin 500mg injection are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aztreonam (500mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of azvin 500mg injection can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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