azifred 500 tablet allopathy (Azithromycin (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
azifred 500 tablet allopathy (Azithromycin (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Fredun Pharmaceuticals Limited. Contains Azithromycin (500mg).

azifred 500 tablet - Uses, Price, Side Effects & Substitutes

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Azithromycin (500mg) (Click to see all medicines with same salt)
🏭 Fredun Pharmaceuticals Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is azifred 500 tablet used for?

Azee 500 Tablet (Azithromycin) is used to treat Respiratory tract infections. It contains Azithromycin (500mg), which Binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Azithromycin
  • Manufacturer: Fredun Pharmaceuticals Limited
  • Medicine Form: Allopathy
  • Pregnancy Category: B

🇮🇳 azifred 500 tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

azifred 500 tablet का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Azithromycin (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

📋 Drug Information

Generic Name(s)Azithromycin
Brand NameAzee 500 Tablet
ManufacturerFredun Pharmaceuticals Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolides
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; bioavailability approximately 37%.
DistributionWidely distributed into tissues and cells; high intracellular concentrations.
Protein Binding7-50% (concentration-dependent, decreases at higher concentrations)
MetabolismPrimarily hepatic, via demethylation; not extensively metabolized.
Half-Life68 hours (terminal half-life)
ExcretionBiliary excretion as unchanged drug and metabolites; renal excretion about 6%.
Bioavailability37% (oral)
Onset of Action1-2 hours
Peak Plasma Time2-3 hours
Duration of Action24 hours (once daily dosing)

Pharmacodynamics

Mechanism of ActionBinds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.
Target Receptor50S ribosomal subunit
Pharmacodynamic EffectsBacteriostatic; inhibits protein synthesis, leading to bacterial growth suppression.

💡 How and when to take azifred 500 tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How azifred 500 tablet Works

Binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.

1 Azithromycin enters bacterial cell via passive diffusion.
⬇️
2 Binds to 50S ribosomal subunit at the 23S rRNA.
⬇️
3 Inhibits translocation of peptidyl-tRNA from A site to P site.
⬇️
4 Blocks protein synthesis, leading to bacteriostatic effect.

💊 azifred 500 tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Respiratory tract infections, Skin and soft tissue infections, Otitis media, Pharyngitis/tonsillitis, Urethritis/cervicitis due to Chlamydia trachomatis, Mycobacterium avium complex prophylaxis in HIV

Off-label uses: Acute exacerbation of COPD, Non-gonococcal urethritis, Pertussis, Babesiosis (with atovaquone)

⚠️ What are the side effects of azifred 500 tablet?

✅ Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache

🚨 Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Severe allergic reactions
  • Hepatotoxicity
  • Clostridioides difficile-associated diarrhea

⚠️ Rare Side Effects

  • Hearing loss (reversible)
  • Acute interstitial nephritis
  • Pancreatitis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Minor
Minor
Minor
Minor
Minor
Minor
Minor
Minor

🚨 Major Interactions

  • Warfarin (increased INR)
  • Ergot derivatives (ergotism)
  • Nelfinavir (increased azithromycin levels)

⚡ Moderate Interactions

  • Digoxin (increased digoxin levels)
  • Cyclosporine (increased cyclosporine levels)
  • Antacids (decreased absorption)

ℹ️ Minor Interactions

  • Theophylline (minor increase)
  • Triazolam (minor increase)

🍽️ Food Interactions

Take on empty stomach (1 hour before or 2 hours after food) for optimal absorption; food may decrease absorption slightly.

🍷 Alcohol Interaction

No direct interaction; but alcohol may increase gastrointestinal side effects.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to azithromycin or any macrolide antibiotic, History of cholestatic jaundice/hepatic dysfunction with prior azithromycin use, QT prolongation or concurrent use of QT-prolonging agents

📊 Monitoring Parameters

Liver function tests (LFT), ECG for QT interval if at risk, Signs of hypersensitivity

🤱 Lactation Safety

Lactation: Limited data; caution advised. Excreted in breast milk in small amounts.

💊 Overdose Management

Supportive care; no specific antidote. Monitor ECG for QT prolongation.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

🛑 Myths vs. Facts about azifred 500 tablet

  • Myth: Generic substitutes of azifred 500 tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Azithromycin (500mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of azifred 500 tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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