azel 40mg capsule allopathy (Enzalutamide (40mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
azel 40mg capsule allopathy (Enzalutamide (40mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Dr Reddy's Laboratories Ltd. Contains Enzalutamide (40mg).

azel 40mg capsule - Uses, Price, Side Effects & Substitutes

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Enzalutamide (40mg) (Click to see all medicines with same salt)
🏭 Dr Reddy's Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is azel 40mg capsule used for?

Azel 80 Capsule (Enzalutamide) is used to treat Metastatic castration-resistant prostate cancer (mCRPC). It contains Enzalutamide (40mg), which Androgen receptor inhibitor; inhibits androgen binding, nuclear translocation, a. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Enzalutamide
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 azel 40mg capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)

azel 40mg capsule का उपयोग मुख्य रूप से anti neoplastics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Enzalutamide (40mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Azel 40mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Enzalutamide
Brand NameAzel 80 Capsule
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAndrogen receptor antagonist
Route of AdministrationOral.
StorageStore at 20-25°C (68-77°F); protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; bioavailability approximately 84%.
DistributionExtensively distributed; volume of distribution about 110 L.
Protein Binding97-98% bound to plasma proteins.
MetabolismPrimarily metabolized by CYP2C8 and CYP3A4 to active metabolite N-desmethyl enzalutamide.
Half-LifeEnzalutamide: 5.8 days; N-desmethyl enzalutamide: 7.8-8.6 days.
ExcretionPrimarily fecal (71%) and renal (14%) as metabolites.
BioavailabilityApproximately 84%.
Onset of ActionNot well defined; steady state reached in about 1 month.
Peak Plasma Time1-2 hours post-dose.
Duration of ActionLong duration due to long half-life.

Pharmacodynamics

Mechanism of ActionAndrogen receptor inhibitor; inhibits androgen binding, nuclear translocation, and DNA interaction.
Target ReceptorAndrogen receptor (AR).
Pharmacodynamic EffectsReduces prostate-specific antigen (PSA) levels, inhibits tumor growth.

💡 How and when to take azel 40mg capsule?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from moisture.

⚙️ How azel 40mg capsule Works

Androgen receptor inhibitor; inhibits androgen binding, nuclear translocation, and DNA interaction.

1 Binds to androgen receptor (AR) with high affinity
⬇️
2 Inhibits androgen binding to AR
⬇️
3 Prevents AR nuclear translocation
⬇️
4 Inhibits AR interaction with DNA
⬇️
5 Reduces AR-mediated gene transcription
⬇️
6 Decreases prostate cancer cell proliferation and induces apoptosis

💊 azel 40mg capsule Uses in Hindi (Ke Fayde), Benefits & Indications

Metastatic castration-resistant prostate cancer (mCRPC), non-metastatic castration-resistant prostate cancer (nmCRPC).

Off-label uses: Breast cancer (AR-positive), other AR-dependent cancers.

⚠️ What are the side effects of azel 40mg capsule?

✅ Common Side Effects

  • Fatigue
  • Hypertension
  • Hot flush
  • Headache
  • Diarrhea

🚨 Serious Side Effects

  • Seizures
  • Posterior reversible encephalopathy syndrome (PRES)
  • Hypersensitivity reactions

⚠️ Rare Side Effects

  • Interstitial lung disease
  • Hepatic failure

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for azel 40mg capsule

View All

Alternative brands with exact same active ingredient and strength (Enzalutamide (40mg)):

  1. capmide 40mg capsule
    Cipla Ltd₹862.50💰 89.4% CHEAPER
  2. xylutide 40mg capsule
    Cipla Ltd₹1,012.00💰 87.6% CHEAPER
  3. enzana capsule
    Hetero Healthcare Limited₹5,700.00💰 30.1% CHEAPER
  4. obnyx capsule
    Zydus Cadila₹5,995.00💰 26.5% CHEAPER
  5. enzyl capsule
    Sun Pharmaceutical Industries Ltd₹6,440.00💰 21% CHEAPER
  6. xylutide capsule
    Cipla Ltd₹6,440.00💰 21% CHEAPER
  7. enzamide 40mg tablet
    Intas Pharmaceuticals Ltd₹11,500.00📈 41% COSTLIER
  8. bdenza 40mg capsule
    Prakash Biopharma₹16,859.92📈 106.7% COSTLIER
  9. glenza capsule
    Glenmark Pharmaceuticals Ltd₹20,100.00📈 146.4% COSTLIER
  10. encrpc 40mg capsule
    Intas Pharmaceuticals Ltd₹20,298.72📈 148.9% COSTLIER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
CYP2C8 substrates Major Increased substrate exposure
CYP3A4 substrates Major Increased substrate exposure
CYP2C9 substrates Moderate Altered substrate levels
CYP2C19 substrates Moderate Altered substrate levels
P-glycoprotein substrates Moderate Increased substrate exposure

🚨 Major Interactions

  • CYP2C8 substrates
  • CYP3A4 substrates
  • Warfarin

⚡ Moderate Interactions

  • CYP2C9 substrates
  • CYP2C19 substrates
  • P-glycoprotein substrates

ℹ️ Minor Interactions

  • CYP1A2 substrates

🍽️ Food Interactions

No significant food interactions; avoid grapefruit juice (CYP3A4 inhibitor).

🍷 Alcohol Interaction

No specific interaction; caution due to CNS effects.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, hypersensitivity to enzalutamide.

📊 Monitoring Parameters

PSA levels, liver function tests, blood pressure, seizure risk.

🤱 Lactation Safety

Not recommended; unknown if excreted in human milk.

💊 Overdose Management

No specific antidote; supportive care.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose.

🛑 Myths vs. Facts about azel 40mg capsule

  • Myth: Generic substitutes of azel 40mg capsule are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Enzalutamide (40mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of azel 40mg capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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