axicard 20mg tablet - Isosorbide Mononitrate (20mg) medicine

Axicard 20mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Axis Life Science Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is axicard 20mg tablet used for?

Axicard 20mg Tablet contains Isosorbide Mononitrate, a nitrate vasodilator used to prevent angina (chest pain) by relaxing blood vessels and improving blood flow to the heart. It is typically taken twice daily, with doses in the morning and evening, to maintain consistent protection.

  • Generic Name: Isosorbide Mononitrate
  • Manufacturer: Axis Life Science Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š axicard 20mg tablet Uses & Benefits

Prophylaxis of angina pectoris, congestive heart failure (adjunct)

Off-label uses: Esophageal spasm, anal fissures

๐Ÿ“‹ Drug Information

Generic Name(s)Isosorbide Mononitrate
Brand NameAngicor
ManufacturerAxis Life Science Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassNO Donors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract
DistributionDistributed throughout the body; volume of distribution approximately 0.6 L/kg
Protein BindingLess than 5%
MetabolismExtensively metabolized in the liver to inactive metabolites
Half-Life4-5 hours
ExcretionPrimarily renal (urine) as metabolites
BioavailabilityApproximately 90%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Relaxes vascular smooth muscle via nitric oxide-mediated increase in cyclic guanosine monophosphate (cGMP)

Mechanism Steps

1Isosorbide mononitrate is denitrated to release nitric oxide (NO)
2NO activates guanylate cyclase in vascular smooth muscle cells
3Increased cGMP levels lead to relaxation of smooth muscle

๐Ÿ’ก How to Take axicard 20mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of axicard 20mg tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Hypotension
  • Flushing
  • Nausea

๐Ÿšจ Serious Side Effects

  • Severe hypotension
  • Syncope
  • Methemoglobinemia (rare)

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Sildenafil Major Severe hypotension
Alcohol Moderate Increased hypotension and dizziness
Aspirin Minor Increased antiplatelet effect

๐Ÿšจ Major Interactions

  • Sildenafil
  • Tadalafil
  • Vardenafil
  • Riociguat

โšก Moderate Interactions

  • Antihypertensives
  • Alcohol
  • Beta-blockers
  • Calcium channel blockers

โ„น๏ธ Minor Interactions

  • Aspirin
  • Heparin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not affect bioavailability

๐Ÿท Alcohol Interaction

Additive vasodilation and hypotension

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity, severe hypotension, cardiogenic shock, concurrent use with PDE5 inhibitors or riociguat

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, symptom relief

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Supportive care; monitor blood pressure; administer vasopressors if needed

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for axicard 20mg tablet

View All

Alternative brands with exact same active ingredient (Isosorbide Mononitrate (20mg)):

Medical Note: Always consult your doctor before switching medications.

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