avril 2mg/500mg/10mg tablet - Chlorpheniramine Maleate (2mg) + Paracetamol (500mg) medicine

avril 2mg/500mg/10mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Avilius Neutracare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is avril 2mg/500mg/10mg tablet used for?

Alex P Syrup (Chlorpheniramine Maleate + Paracetamol) is used to treat RESPIRATORY. It contains Chlorpheniramine Maleate (2mg) + Paracetamol (500mg), which Chlorpheniramine: H1-receptor antagonist; Paracetamol: COX inhibition in CNS. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chlorpheniramine Maleate + Paracetamol
  • Manufacturer: Avilius Neutracare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š avril 2mg/500mg/10mg tablet Uses & Benefits

Allergic rhinitis, common cold, fever, mild pain

Off-label uses: Urticaria, motion sickness (Chlorpheniramine)

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorpheniramine Maleate + Paracetamol
Brand NameAlex P Syrup
ManufacturerAvilius Neutracare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract
DistributionWidely distributed throughout body
Protein BindingChlorpheniramine: 70%; Paracetamol: 25%
MetabolismChlorpheniramine: Hepatic via CYP450; Paracetamol: Hepatic via conjugation
Half-LifeChlorpheniramine: 21-27 hours; Paracetamol: 2-3 hours
ExcretionRenal (urine)
BioavailabilityChlorpheniramine: 25-50%; Paracetamol: 85-90%
Onset of ActionChlorpheniramine: 30-60 min; Paracetamol: 30-60 min
Peak Plasma TimeChlorpheniramine: 2-6 hours; Paracetamol: 30-60 min
Duration of ActionChlorpheniramine: 4-6 hours; Paracetamol: 4-6 hours

How It Works

Chlorpheniramine: H1-receptor antagonist; Paracetamol: COX inhibition in CNS

Mechanism Steps

1Chlorpheniramine competitively blocks H1 receptors, preventing histamine-mediated effects
2Paracetamol inhibits COX enzymes in the CNS, reducing prostaglandin synthesis
3Decreased prostaglandin leads to antipyretic and analgesic effects

๐Ÿ’ก How to Take avril 2mg/500mg/10mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of avril 2mg/500mg/10mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Nausea
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Severe allergic reaction
  • Blood dyscrasias

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased anticholinergic and CNS effects
Alcohol Major Increased CNS depression and hepatotoxicity
CNS depressants Major Additive sedation
Warfarin Moderate Increased INR with high doses of paracetamol
Isoniazid Moderate Increased hepatotoxicity risk
Rifampin Moderate Reduced paracetamol efficacy
Anticholinergics Minor Additive anticholinergic effects
Corticosteroids Minor Increased intraocular pressure risk

๐Ÿšจ Major Interactions

  • MAOIs
  • Alcohol
  • CNS depressants

โšก Moderate Interactions

  • Warfarin
  • Isoniazid
  • Rifampin

โ„น๏ธ Minor Interactions

  • Anticholinergics
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

Avoid alcohol, No significant food interactions

๐Ÿท Alcohol Interaction

Increased CNS depression and hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, MAOI use

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, CBC

๐Ÿคฑ Lactation Safety

Use with caution; small amounts excreted in breast milk

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

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