atorsave d 20 tablet - Atorvastatin (20mg) + Vitamin D3 (1000IU) medicine

atorsave d 20 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Eris Lifesciences Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 22, 2026

What is atorsave d 20 tablet used for?

Atorsave D 10 Tablet (Atorvastatin + Vitamin D3) is used to treat CARDIAC. It contains Atorvastatin (20mg) + Vitamin D3 (1000IU), which Atorvastatin competitively inhibits HMG-CoA reductase, reducing cholesterol synt. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Atorvastatin + Vitamin D3
  • Manufacturer: Eris Lifesciences Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š atorsave d 20 tablet Uses & Benefits

Primary hypercholesterolemia, mixed dyslipidemia, homozygous familial hypercholesterolemia, prevention of cardiovascular events, vitamin D deficiency or insufficiency.

Off-label uses: Polycystic ovary syndrome (PCOS), non-alcoholic fatty liver disease (NAFLD), prevention of contrast-induced nephropathy (atorvastatin), osteoporosis (vitamin D3).

๐Ÿ“‹ Drug Information

Generic Name(s)Atorvastatin + Vitamin D3
Brand NameAtorsave D 10 Tablet
ManufacturerEris Lifesciences Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassHMG-CoA reductase inhibitor (statin) with vitamin D supplementation
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAtorvastatin is rapidly absorbed after oral administration; peak plasma concentrations occur within 1-2 hours. Vitamin D3 is well absorbed in the small intestine.
DistributionAtorvastatin is highly distributed to tissues; vitamin D3 is distributed to fat and muscle tissues.
Protein BindingAtorvastatin: โ‰ฅ98% bound to plasma proteins. Vitamin D3: bound to vitamin D-binding protein.
MetabolismAtorvastatin: extensively metabolized by CYP3A4 to active ortho- and para-hydroxylated metabolites. Vitamin D3: hydroxylated in liver to 25-hydroxyvitamin D3.
Half-LifeAtorvastatin: approximately 14 hours (parent drug); active metabolites: 20-30 hours. Vitamin D3: 2-3
ExcretionAtorvastatin: primarily biliary excretion (feces); less than 2% excreted in urine. Vitamin D3: excreted in bile and feces.
BioavailabilityAtorvastatin: approximately 14% (low due to first-pass metabolism). Vitamin D3: well absorbed.
Onset of ActionAtorvastatin: within 2 weeks for lipid-lowering effect. Vitamin D3: variable.
Peak Plasma TimeAtorvastatin: 1-2 hours. Vitamin D3: 12-24 hours.
Duration of ActionAtorvastatin: up to 24 hours (once-daily dosing). Vitamin D3: weeks to months.

How It Works

Atorvastatin competitively inhibits HMG-CoA reductase, reducing cholesterol synthesis; increases LDL receptor expression. Vitamin D3 enhances calcium absorption and bone mineralization.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis.
2Reduced intracellular cholesterol leads to upregulation of LDL receptors on hepatocytes.
3Increased LDL receptor expression enhances clearance of LDL-C from plasma.

๐Ÿ’ก How to Take atorsave d 20 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of atorsave d 20 tablet

โœ… Common Side Effects

  • Nasopharyngitis
  • Arthralgia
  • Diarrhea
  • Pain in extremity
  • Urinary tract infection
  • Dyspepsia
  • Nausea
  • Musculoskeletal pain

๐Ÿšจ Serious Side Effects

  • Rhabdomyolysis
  • Myopathy
  • Hepatotoxicity (elevated transaminases, jaundice)
  • Hypersensitivity reactions (angioedema, Stevens-Johnson syndrome)
  • New-onset diabetes mellitus
  • Hemorrhagic stroke (in patients with prior stroke)

โš ๏ธ Rare Side Effects

  • Interstitial lung disease
  • Peripheral neuropathy
  • Memory loss
  • Confusion
  • Gynecomastia
  • Tendon rupture
  • Immune-mediated necrotizing myopathy

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CYP3A4 inhibitors Major Increased atorvastatin plasma concentration, risk of myopathy/rhabdomyolysis
Cyclosporine Major Increased atorvastatin exposure and risk of toxicity
Gemfibrozil Major Increased risk of myopathy/rhabdomyolysis
Warfarin Moderate Increased INR and bleeding risk
Grapefruit juice Moderate Increased atorvastatin levels
Antacids Moderate Reduced atorvastatin absorption if taken within 2 hours

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, erythromycin, clarithromycin, telithromycin, HIV protease inhibitors, nefazodone)
  • Cyclosporine
  • Gemfibrozil
  • Other fibrates
  • Niacin (โ‰ฅ1 g/day)
  • Colchicine
  • Rifampin
  • Digoxin
  • Oral contraceptives

โšก Moderate Interactions

  • Warfarin
  • Antacids
  • Colestipol
  • Colesevelam
  • Fenofibrate
  • Ezetimibe
  • Amiodarone
  • Verapamil
  • Diltiazem
  • Grapefruit juice

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ranitidine
  • Omeprazole
  • Azithromycin
  • Fluconazole

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice increases atorvastatin exposure; avoid large quantities. Vitamin D3 absorption enhanced with fatty meals.

๐Ÿท Alcohol Interaction

Excessive alcohol consumption may increase risk of hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to atorvastatin or vitamin D3, concomitant use with strong CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, HIV protease inhibitors).

๐Ÿ“Š Monitoring Parameters

Lipid profile (LDL-C, HDL-C, triglycerides), liver function tests (ALT, AST) at baseline and periodically, creatine kinase (CK) if muscle symptoms occur, serum 25-hydroxyvitamin D levels.

๐Ÿคฑ Lactation Safety

Atorvastatin is excreted in breast milk; not recommended during breastfeeding. Vitamin D3 is safe.

๐Ÿ’Š Overdose Management

No specific antidote; symptomatic and supportive care; monitor liver function and CK levels; consider gastric lavage if recent ingestion.

โฐ Missed Dose

Take missed dose as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 22, 2026

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