astibet cream allopathy (Mometasone (0.1% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India
astibet cream allopathy (Mometasone (0.1% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Izng Pharmaceuticals. Contains Mometasone (0.1% w/w).

astibet cream - Uses, Price, Side Effects & Substitutes

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Mometasone (0.1% w/w) (Click to see all medicines with same salt)
🏭 Izng Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is astibet cream used for?

Aquamet 50mcg Nasal Spray (Mometasone) is used to treat Allergic rhinitis (seasonal and perennial). It contains Mometasone (0.1% w/w), which Agonist at glucocorticoid receptor, leading to anti-inflammatory gene transcript. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Mometasone
  • Manufacturer: Izng Pharmaceuticals
  • Medicine Form: Allopathy
  • Pregnancy Category: C

🇮🇳 astibet cream के बारे में संक्षिप्त जानकारी (Hindi Summary)

astibet cream का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Mometasone (0.1% w/w) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Drug Information

Generic Name(s)Mometasone
Brand NameAquamet 50mcg Nasal Spray
ManufacturerIzng Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassGlucocorticoids
Route of AdministrationIntranasal
StorageStore at 20-25°C (68-77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionLow systemic absorption; approximately 0.1% of dose absorbed intranasally
DistributionWidely distributed; volume of distribution not well characterized
Protein Binding98-99% bound to plasma proteins
MetabolismExtensively metabolized in liver via CYP3A4 to multiple metabolites
Half-Life5.8 hours (intravenous); not determined for intranasal
ExcretionPrimarily excreted in feces (74%) and urine (8%) as metabolites
Bioavailability<1% after intranasal administration
Onset of ActionWithin 12 hours; maximal effect in 1-2 weeks
Peak Plasma TimeNot applicable due to low systemic absorption
Duration of Action24 hours

Pharmacodynamics

Mechanism of ActionAgonist at glucocorticoid receptor, leading to anti-inflammatory gene transcription and suppression of inflammatory mediators
Target ReceptorGlucocorticoid receptor (GR)
Pharmacodynamic EffectsReduction of nasal inflammation, congestion, rhinorrhea, sneezing, and itching

💡 How and when to take astibet cream?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light and moisture

⚙️ How astibet cream Works

Agonist at glucocorticoid receptor, leading to anti-inflammatory gene transcription and suppression of inflammatory mediators

1 Mometasone diffuses across cell membrane
⬇️
2 Binds to glucocorticoid receptor in cytoplasm
⬇️
3 Receptor-ligand complex translocates to nucleus
⬇️
4 Binds to glucocorticoid response elements on DNA
⬇️
5 Modulates gene transcription: upregulates anti-inflammatory proteins (e.g., lipocortin-1) and downregulates pro-inflammatory cytokines (e.g., IL-1, IL-6, TNF-alpha)
⬇️
6 Reduces recruitment and activation of inflammatory cells

💊 astibet cream Uses in Hindi (Ke Fayde), Benefits & Indications

Allergic rhinitis (seasonal and perennial), nasal polyps

Off-label uses: Non-allergic rhinitis, acute sinusitis (adjunctive)

⚠️ What are the side effects of astibet cream?

✅ Common Side Effects

  • Headache
  • Epistaxis
  • Pharyngitis
  • Nasal burning
  • Nasal irritation

🚨 Serious Side Effects

  • Adrenal suppression
  • Growth retardation in children
  • Glaucoma
  • Cataracts
  • Nasal septal perforation

⚠️ Rare Side Effects

  • Anaphylaxis
  • Angioedema
  • Bronchospasm
  • Immunosuppression

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Ketoconazole Major Increased systemic mometasone exposure
Ritonavir Major Increased systemic mometasone exposure
Rifampin Major Decreased mometasone efficacy
Warfarin Moderate Potential increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

⚡ Moderate Interactions

  • Anticoagulants (e.g., warfarin)
  • NSAIDs (e.g., aspirin, ibuprofen)

ℹ️ Minor Interactions

  • Oral corticosteroids
  • Vaccines (live attenuated)

🍽️ Food Interactions

No significant food interactions

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to mometasone or any excipients; untreated nasal infection

📊 Monitoring Parameters

Nasal symptoms, signs of adrenal suppression with prolonged use, nasal mucosal examination

🤱 Lactation Safety

Excretion in breast milk unknown; use with caution

💊 Overdose Management

No specific antidote; supportive care; unlikely to require treatment due to low systemic absorption

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose

🛑 Myths vs. Facts about astibet cream

  • Myth: Generic substitutes of astibet cream are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Mometasone (0.1% w/w)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of astibet cream can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

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