asthesia cream - Uses, Price, Side Effects & Substitutes
What is asthesia cream used for?
Asthesia Cream (Prilocaine + Lidocaine) is used to treat PAIN ANALGESICS. It contains Prilocaine (2.5% w/w) + Lidocaine (2.5% w/w), which Stabilizes neuronal membranes by inhibiting sodium ion channels, blocking nerve . Always consult your doctor before use. Take as prescribed.
- Generic Name: Prilocaine + Lidocaine
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ asthesia cream Uses & Benefits
Topical anesthesia for dermal procedures, venipuncture, minor surgery.
Off-label uses: Post-herpetic neuralgia, Mucosal anesthesia
๐ Drug Information
| Generic Name(s) | Prilocaine + Lidocaine |
| Brand Name | Asthesia Cream |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Local Anesthetics |
| Route of Administration | Topical |
| Storage | Store at 20-25ยฐC (68-77ยฐF); do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Stabilizes neuronal membranes by inhibiting sodium ion channels, blocking nerve impulse conduction.
Mechanism Steps
๐ก How to Take asthesia cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of asthesia cream
โ Common Side Effects
- Application site erythema
- Edema
- Itching
๐จ Serious Side Effects
- Methemoglobinemia
- Cardiac arrhythmias
- Seizures
โ ๏ธ Rare Side Effects
- Allergic dermatitis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Class I antiarrhythmics | Major | Increased risk of cardiac toxicity |
| Other local anesthetics | Major | Additive systemic toxicity |
| CYP1A2 inhibitors | Moderate | Increased lidocaine levels |
| CYP3A4 inhibitors | Moderate | Increased lidocaine levels |
| Acetaminophen | Minor | Possible increased methemoglobin risk |
| Beta-blockers | Minor | Reduced lidocaine clearance |
๐จ Major Interactions
- Class I antiarrhythmics
- Other local anesthetics
โก Moderate Interactions
- CYP1A2 inhibitors
- CYP3A4 inhibitors
โน๏ธ Minor Interactions
- Acetaminophen
- Beta-blockers
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase CNS depression.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amide anesthetics, methemoglobinemia, severe hepatic impairment.
๐ Monitoring Parameters
Monitor for signs of systemic toxicity, methemoglobinemia, local reactions.
๐คฑ Lactation Safety
Use with caution; small amounts excreted in breast milk.
๐ Overdose Management
Discontinue use; symptomatic and supportive care; treat methemoglobinemia with methylene blue if needed.
โฐ Missed Dose
Not applicable; apply as needed before procedure.