asmaphylin m 231mg/69mg/10mg tablet sr - Uses, Price, Side Effects & Substitutes
What is asmaphylin m 231mg/69mg/10mg tablet sr used for?
Asmaphylin M 231mg/69mg/10mg Tablet SR (Etofylline + Theophylline) is used to treat RESPIRATORY. It contains Etofylline (231mg) + Theophylline (69mg), which Inhibits phosphodiesterase, increasing cAMP; antagonizes adenosine receptors; en. Always consult your doctor before use. Take as prescribed.
- Generic Name: Etofylline + Theophylline
- Manufacturer: ICI Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ asmaphylin m 231mg/69mg/10mg tablet sr Uses & Benefits
Bronchial asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions with bronchospasm.
Off-label uses: Apnea of prematurity, Postoperative respiratory depression
๐ Drug Information
| Generic Name(s) | Etofylline + Theophylline |
| Brand Name | Asmaphylin M 231mg/69mg/10mg Tablet SR |
| Manufacturer | ICI Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Xanthine bronchodilator |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits phosphodiesterase, increasing cAMP; antagonizes adenosine receptors; enhances mucociliary clearance.
Mechanism Steps
๐ก How to Take asmaphylin m 231mg/69mg/10mg tablet sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of asmaphylin m 231mg/69mg/10mg tablet sr
โ Common Side Effects
- Nausea
- Vomiting
- Headache
- Insomnia
- Nervousness
- Tachycardia
๐จ Serious Side Effects
- Seizures
- Arrhythmias
- Severe hypotension
- Respiratory arrest
โ ๏ธ Rare Side Effects
- Hyperglycemia
- Hypokalemia
- Rhabdomyolysis
- Allergic reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cimetidine | Major | Decreased theophylline clearance, increased toxicity risk. |
| Ciprofloxacin | Major | Increased theophylline levels, risk of seizures. |
| Erythromycin | Major | Increased theophylline levels, toxicity. |
| Fluvoxamine | Major | Markedly increased theophylline levels. |
| Methotrexate | Major | Increased theophylline levels. |
| Propranolol | Major | Reduced theophylline clearance, antagonism of bronchodilation. |
| Carbamazepine | Moderate | Decreased theophylline levels. |
| Phenytoin | Moderate | Decreased theophylline levels. |
| Rifampin | Moderate | Decreased theophylline levels. |
| Smoking | Moderate | Increased theophylline metabolism, reduced efficacy. |
| St. John's Wort | Moderate | Decreased theophylline levels. |
| Allopurinol | Minor | Slight increase in theophylline levels. |
| Benzodiazepines | Minor | Possible additive CNS depression. |
| Disulfiram | Minor | Decreased theophylline clearance. |
| Interferon | Minor | Decreased theophylline clearance. |
| Verapamil | Minor | Increased theophylline levels. |
๐จ Major Interactions
- Cimetidine
- Ciprofloxacin
- Erythromycin
- Fluvoxamine
- Methotrexate
- Propranolol
โก Moderate Interactions
- Carbamazepine
- Phenytoin
- Rifampin
- Smoking (tobacco/marijuana)
- St. John's Wort
โน๏ธ Minor Interactions
- Allopurinol
- Benzodiazepines
- Disulfiram
- Interferon
- Verapamil
๐ฝ๏ธ Food Interactions
High-fat meals may delay absorption; charcoal-broiled foods increase metabolism; caffeine-containing foods may increase side effects.
๐ท Alcohol Interaction
Alcohol may increase theophylline metabolism and reduce efficacy; also may increase risk of seizures.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to xanthines, active peptic ulcer, seizure disorders (unless controlled), severe cardiac arrhythmias.
๐ Monitoring Parameters
Serum theophylline levels (therapeutic range 10-20 mcg/mL), heart rate, respiratory rate, CNS symptoms.
๐คฑ Lactation Safety
Use with caution; theophylline excreted in breast milk; may cause irritability in infants.
๐ Overdose Management
Activated charcoal, supportive care, monitoring of serum theophylline levels; severe cases may require hemodialysis.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.