Asmabron-N Tablet - Uses, Price, Side Effects
What is asmabron-n tablet used for?
Asmabron-N Tablet is a combination of Montelukast (10mg) and Theophylline (400mg) used to prevent and treat asthma and COPD symptoms. Montelukast blocks leukotrienes to reduce airway inflammation, while Theophylline relaxes bronchial muscles, improving breathing. It is taken twice daily as prescribed.
- Generic Name: Montelukast + Theophylline
- Manufacturer: Overseas Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ asmabron-n tablet Uses & Benefits
Prophylaxis and chronic treatment of asthma, nocturnal asthma, exercise-induced bronchoconstriction.
Off-label uses: Allergic rhinitis, Urticaria
๐ Drug Information
| Generic Name(s) | Montelukast + Theophylline |
| Brand Name | Asmabron-N Tablet |
| Manufacturer | Overseas Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Leukotriene receptor antagonist + Xanthine bronchodilator |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Montelukast: Blocks leukotriene D4 receptors; Theophylline: Inhibits phosphodiesterase, increases cAMP.
Mechanism Steps
๐ก How to Take asmabron-n tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of asmabron-n tablet
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Insomnia
๐จ Serious Side Effects
- Seizures
- Arrhythmias
- Stevens-Johnson syndrome
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Churg-Strauss syndrome
- Pulmonary eosinophilia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Cimetidine | Moderate | Increased theophylline levels |
| Phenytoin | Moderate | Decreased theophylline effect |
๐จ Major Interactions
- CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
- CYP3A4 inducers (e.g., rifampin)
- Lithium
- Warfarin
โก Moderate Interactions
- Phenytoin
- Carbamazepine
- Oral contraceptives
- Beta-blockers
โน๏ธ Minor Interactions
- Caffeine
- Theophylline-containing products
- Zafirlukast
๐ฝ๏ธ Food Interactions
High-fat meals may decrease absorption of montelukast; Theophylline absorption affected by food (avoid charcoal-broiled foods).
๐ท Alcohol Interaction
Alcohol may increase theophylline clearance.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, porphyria, active peptic ulcer, seizure disorders (theophylline).
๐ Monitoring Parameters
Peak expiratory flow, serum theophylline levels, liver function, ECG.
๐คฑ Lactation Safety
Montelukast: Excreted in milk, use with caution; Theophylline: Excreted in milk, may cause irritability in infant.
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; monitor cardiac and CNS effects.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.