asar-ct 40/6.25 tablet - Uses, Price, Side Effects & Substitutes
What is asar-ct 40/6.25 tablet used for?
Asar-CT 40/12.5 Tablet (Azilsartan medoxomil + Chlorthalidone) is used to treat Hypertension (alone or in combination).. It contains Azilsartan medoxomil (40mg) + Chlorthalidone (6.25mg), which Azilsartan blocks AT1 receptor, reducing vasoconstriction and aldosterone secret. Always consult your doctor before use. Take as prescribed.
- Generic Name: Azilsartan medoxomil + Chlorthalidone
- Manufacturer: Glenmark Pharmaceuticals Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 asar-ct 40/6.25 tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
asar-ct 40/6.25 tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Azilsartan medoxomil (40mg) + Chlorthalidone (6.25mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Azilsartan medoxomil + Chlorthalidone |
|---|---|
| Brand Name | Asar-CT 40/12.5 Tablet |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II receptor blocker (ARB) + Thiazide-like diuretic |
| Route of Administration | Oral |
| Storage | Store at 20-25°C (68-77°F); protect from moisture and light. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take asar-ct 40/6.25 tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F); protect from moisture and light.
⚙️ How asar-ct 40/6.25 tablet Works
Azilsartan blocks AT1 receptor, reducing vasoconstriction and aldosterone secretion; Chlorthalidone inhibits Na+/Cl- cotransporter in distal tubule, increasing diuresis.
💊 asar-ct 40/6.25 tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Hypertension (alone or in combination).
Off-label uses: Heart failure (limited data).
⚠️ What are the side effects of asar-ct 40/6.25 tablet?
✅ Common Side Effects
- Dizziness
- Fatigue
- Diarrhea
- Hypokalemia
- Hyperuricemia
🚨 Serious Side Effects
- Angioedema
- Acute renal failure
- Hyperkalemia
- Hypotension
- Syncope
⚠️ Rare Side Effects
- Hepatotoxicity
- Pancreatitis
- Stevens-Johnson syndrome
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | Increased lithium toxicity risk |
| NSAIDs | Major | Reduced antihypertensive effect, increased renal impairment risk |
| ACE inhibitors | Major | Increased risk of hypotension, hyperkalemia, renal dysfunction |
| Aliskiren | Major | Increased risk of hypotension, hyperkalemia, renal dysfunction |
| Potassium-sparing diuretics | Major | Increased risk of hyperkalemia |
| Corticosteroids | Moderate | Reduced diuretic effect |
| Amphotericin B | Moderate | Increased risk of hypokalemia |
| Loop diuretics | Moderate | Additive diuretic effect, electrolyte imbalance |
| Dofetilide | Moderate | Increased risk of torsades de pointes due to hypokalemia |
| Antidiabetic agents | Minor | May alter blood glucose control |
| Alcohol | Minor | Additive hypotensive effect |
| Barbiturates | Minor | Additive hypotensive effect |
🚨 Major Interactions
- Lithium
- NSAIDs
- ACE inhibitors
- Aliskiren
- Potassium-sparing diuretics
⚡ Moderate Interactions
- Corticosteroids
- Amphotericin B
- Loop diuretics
- Dofetilide
ℹ️ Minor Interactions
- Antidiabetic agents
- Alcohol
- Barbiturates
🍽️ Food Interactions
Avoid high-potassium foods; take with or without food.
🍷 Alcohol Interaction
May potentiate orthostatic hypotension.
🛡️ Safety & Warnings
🚫 Contraindications
Anuria, hypersensitivity to sulfonamides, severe renal impairment (CrCl <30 mL/min), pregnancy.
📊 Monitoring Parameters
Blood pressure, serum potassium, renal function, blood glucose, uric acid.
🤱 Lactation Safety
Not recommended; Chlorthalidone excreted in milk, Azilsartan unknown.
💊 Overdose Management
Symptomatic and supportive; monitor electrolytes, BP, renal function; consider gastric lavage.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
🛑 Myths vs. Facts about asar-ct 40/6.25 tablet
- Myth: Generic substitutes of asar-ct 40/6.25 tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Azilsartan medoxomil (40mg) + Chlorthalidone (6.25mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of asar-ct 40/6.25 tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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