ariliz 600mg tablet - Linezolid (600mg) medicine

ariliz 600mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Sarian Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is ariliz 600mg tablet used for?

Alinzo 600mg Tablet (Linezolid) is used to treat ANTI INFECTIVES. It contains Linezolid (600mg), which Inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Linezolid
  • Manufacturer: Sarian Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š ariliz 600mg tablet Uses & Benefits

Vancomycin-resistant Enterococcus faecium infections, Nosocomial pneumonia, Community-acquired pneumonia, Complicated skin and soft tissue infections, Uncomplicated skin infections

Off-label uses: Tuberculosis (multidrug-resistant), Nocardiosis, Bone and joint infections, Prosthetic joint infections

๐Ÿ“‹ Drug Information

Generic Name(s)Linezolid
Brand NameAlinzo 600mg Tablet
ManufacturerSarian Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassOxazolidinone
Route of AdministrationOral (tablet or suspension) or intravenous.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and extensively absorbed after oral administration, with absolute bioavailability approximately 100%.
DistributionWidely distributed to well-perfused tissues, including lungs, skin, and soft tissues. Volume of distribution ~40-50 L.
Protein BindingApproximately 31% bound to plasma proteins.
MetabolismPrimarily metabolized by oxidation of the morpholine ring, forming two inactive metabolites: aminoethoxyacetic acid and hydroxyethyl glycine. Metabolism is not CYP450-dependent.
Half-LifeApproximately 4-5 hours.
ExcretionRenal excretion: ~30% unchanged drug, ~50% as metabolites. Fecal excretion: ~10%.
Bioavailability~100% (oral and IV).
Onset of ActionRapid; within 1-2 hours after oral administration.
Peak Plasma Time1-2 hours after oral dose.
Duration of ActionApproximately 12 hours (dosing interval 12 hours).

How It Works

Inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit, preventing formation of the 70S initiation complex.

Mechanism Steps

1Linezolid binds to the 23S rRNA of the 50S ribosomal subunit.
2Prevents the formation of the 70S initiation complex.
3Inhibits bacterial protein synthesis at the initiation phase.

๐Ÿ’ก How to Take ariliz 600mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ariliz 600mg tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Loose stools

๐Ÿšจ Serious Side Effects

  • Myelosuppression (thrombocytopenia, anemia, leukopenia)
  • Serotonin syndrome
  • Lactic acidosis
  • Peripheral neuropathy
  • Optic neuropathy
  • Clostridioides difficile colitis

โš ๏ธ Rare Side Effects

  • Seizures
  • QT prolongation
  • Pancreatitis
  • Renal failure
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
SSRIs (e.g., fluoxetine) Major Increased risk of serotonin syndrome
MAOIs (e.g., phenelzine) Major Increased risk of serotonin syndrome
Warfarin Moderate Potential increased INR; monitor closely
Rifampin Moderate Decreased linezolid exposure

๐Ÿšจ Major Interactions

  • MAO inhibitors
  • Serotonergic drugs (e.g., SSRIs, SNRIs, TCAs, MAOIs)
  • Sympathomimetic agents
  • Vasopressors
  • Dopaminergic agents

โšก Moderate Interactions

  • Warfarin
  • Rifampin
  • CYP3A4 inducers

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Antacids

๐Ÿฝ๏ธ Food Interactions

Avoid high-tyramine foods (aged cheese, cured meats, fermented products) due to risk of hypertensive crisis.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase risk of lactic acidosis and CNS effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to linezolid, Concurrent use of MAOIs or within 2 weeks of MAOI therapy, Uncontrolled hypertension, Pheochromocytoma, Carcinoid syndrome, Thyrotoxicosis

๐Ÿ“Š Monitoring Parameters

Complete blood count (CBC) weekly due to myelosuppression, Blood pressure, Signs of serotonin syndrome, Lactic acid levels if symptoms occur

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised. Discontinue nursing or drug based on importance.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote. Hemodialysis may remove ~30% of dose.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose. Do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for ariliz 600mg tablet

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Alternative brands with exact same active ingredient (Linezolid (600mg)):

Medical Note: Always consult your doctor before switching medications.

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