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arflex mr 60mg/4mg tablet allopathy (Etoricoxib (60mg) + Thiocolchicoside (4mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
arflex mr 60mg/4mg tablet allopathy (Etoricoxib (60mg) + Thiocolchicoside (4mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Arpsy Life Science Private Limited. Contains Etoricoxib (60mg) + Thiocolchicoside (4mg).

Arflex MR 60mg/4mg Tablet - Uses, Price, Side Effects

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🏭 Arpsy Life Science Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is arflex mr 60mg/4mg tablet used for?

Arflex MR 60mg/4mg Tablet is a combination medicine containing Etoricoxib (a painkiller) and Thiocolchicoside (a muscle relaxant). It is used to relieve pain and muscle spasms associated with musculoskeletal conditions such as back pain, neck pain, and joint pain. Etoricoxib works by reducing inflammation and pain, while Thiocolchicoside helps relax tense muscles.

  • Generic Name: Etoricoxib + Thiocolchicoside
  • Manufacturer: Arpsy Life Science Private Limited
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 arflex mr 60mg/4mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

arflex mr 60mg/4mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Etoricoxib (60mg) + Thiocolchicoside (4mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Etoricoxib + Thiocolchicoside
Brand NameAlock E TH 60mg/4mg Tablet
ManufacturerArpsy Life Science Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Muscle Relaxant
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture and light.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionEtoricoxib: Well absorbed orally; Thiocolchicoside: Rapidly absorbed after oral administration.
DistributionEtoricoxib: Extensively distributed; Thiocolchicoside: Distributed widely, crosses blood-brain barrier.
Protein BindingEtoricoxib: >99% bound to plasma proteins; Thiocolchicoside: ~13% bound.
MetabolismEtoricoxib: Hepatic via CYP3A4; Thiocolchicoside: Hepatic, primarily glucuronidation.
Half-LifeEtoricoxib: ~22 hours; Thiocolchicoside: ~7 hours.
ExcretionEtoricoxib: Renal and fecal; Thiocolchicoside: Renal (70-80% as metabolites).
BioavailabilityEtoricoxib: ~100%; Thiocolchicoside: ~25%.
Onset of ActionEtoricoxib: 1 hour; Thiocolchicoside: 30 minutes.
Peak Plasma TimeEtoricoxib: 1 hour; Thiocolchicoside: 0.5-1 hour.
Duration of ActionEtoricoxib: 24 hours; Thiocolchicoside: 6-8 hours.

Pharmacodynamics

Mechanism of ActionEtoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation.
Target ReceptorEtoricoxib: COX-2 enzyme; Thiocolchicoside: GABA-A and glycine receptors.
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic (etoricoxib); Muscle relaxant (thiocolchicoside).

📅 When to take arflex mr 60mg/4mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take arflex mr 60mg/4mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture and light.

⚙️ How arflex mr 60mg/4mg tablet Works

Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation.

1 Etoricoxib selectively inhibits COX-2, reducing prostaglandin synthesis from arachidonic acid.
⬇️
2 Decreased prostaglandins lead to reduced inflammation, pain, and fever.
⬇️
3 Thiocolchicoside binds to GABA-A receptors, enhancing chloride ion influx and neuronal inhibition.
⬇️
4 Also acts as a glycine receptor agonist, contributing to muscle relaxation.
⬇️
5 Combined effect: analgesia and muscle relaxation.

💊 arflex mr 60mg/4mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle spasms.

Off-label uses: Chronic low back pain, fibromyalgia (limited evidence).

⚠️ What are the side effects of arflex mr 60mg/4mg tablet?

✅ Common Side Effects

  • Nausea
  • Dyspepsia
  • Diarrhea
  • Headache
  • Dizziness
  • Somnolence

🚨 Serious Side Effects

  • GI bleeding
  • Cardiovascular events (MI, stroke)
  • Hepatotoxicity
  • Renal failure
  • Anaphylaxis

⚠️ Rare Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Aplastic anemia
  • Seizures

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for arflex mr 60mg/4mg tablet

View All

Alternative medicines with exact same composition and strength (Etoricoxib (60mg) + Thiocolchicoside (4mg)):

  1. z cox th 60mg/4mg tablet
    Arlak Biotech Pvt Ltd₹45.00💰 76.6% CHEAPER
  2. thio eto 60mg/4mg tablet
    Cure Quick Pharmaceuticals₹59.00💰 69.3% CHEAPER
  3. etovero t 60mg/4mg tablet
    Biorika Healthcare₹75.00💰 61% CHEAPER
  4. davaindia etoricoxib+thiocolchicoside 60mg/4mg tablet
    Davaindia Generic Pharmacy₹75.00💰 61% CHEAPER
  5. etodose th 60mg/4mg tablet
    Bioshine Healthcare Pvt Ltd₹90.00💰 53.2% CHEAPER
  6. yaxoflex 60mg/4mg tablet
    Yaxon BioCare Pvt Ltd₹95.00💰 50.6% CHEAPER
  7. etorbee-ch 60mg/4mg tablet
    Bonsai Pharma₹100.00💰 48% CHEAPER
  8. etoflem plus 60mg/4mg tablet
    Netprime Pharma Pvt Ltd₹110.00💰 42.8% CHEAPER
  9. etorimon t 60mg/4mg tablet
    Edmund Healthcare₹110.00💰 42.8% CHEAPER
  10. stayhappi etoricoxib+thiocolchicoside 60mg/4mg tablet
    Sarvagunaushdhi Pvt Ltd₹110.00💰 42.8% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium toxicity risk

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics
  • Aspirin

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)
  • Anticoagulants
  • Antiplatelets

ℹ️ Minor Interactions

  • Antacids
  • Corticosteroids

🍽️ Food Interactions

Food may delay absorption of etoricoxib but does not affect extent; thiocolchicoside absorption unaffected.

🍷 Alcohol Interaction

Increased risk of gastrointestinal bleeding and hepatotoxicity.

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
High
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity, pregnancy, breastfeeding, severe hepatic/renal impairment, active peptic ulcer, history of asthma, CV disease (etoricoxib), myasthenia gravis (thiocolchicoside).

📊 Monitoring Parameters

Liver function, renal function, blood pressure, signs of GI bleeding, cardiovascular status.

🤱 Lactation Safety

Not recommended; both drugs excreted in breast milk.

💊 Overdose Management

Symptomatic and supportive; no specific antidote. Induce emesis or gastric lavage if recent.

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose. Do not double dose.

🛑 Myths vs. Facts about arflex mr 60mg/4mg tablet

  • Myth: Generic substitutes of arflex mr 60mg/4mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Etoricoxib (60mg) + Thiocolchicoside (4mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of arflex mr 60mg/4mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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Namaste ji. Main Om Prakash Gupta, 70 saal ka, retired teacher hoon. Kal raat meri neck collar laga kar sone ki koshish ki, lekin mujhe usse koi aaram nahi mila. Uski jagah toh gardan aur mooh aur bhi zyada akad gaya. Bahut bechaini hui. Pichle kuch mahino se cervical spondylosis ki wajah se haathon mein sunnapan aur shoulder mein dard rahta hai. Doctor ne collar pehenne ko kaha tha, lekin lagta hai yeh mere liye nahi hai. Ghar mein bivi ko bhi yehi problem hai, unka bhi dard badh gaya hai. Hum dono ek dusre ki madad karte hain, lekin ab toh roz ka kaam bhi mushkil ho raha hai. Beta bahar job karta hai, phone pe kehta hai 'rest karo', par rest se kya hota hai? Yoga aur homeopathy se bahut umeed hai. Kya kisi ko collar se aaram mila hai? Ya koi doosra upay bata sakte hain? Dard se toh mera mann udd gaya hai.

Bhai, neend udd gayi, job gayi, ab kya karein? Free counseling ka koi solution hai?

Bhai log, kal raat phir se neend nahi aayi. 3 baje tak aankhein khuli rahi, bas chhat ki taraf dekh raha tha. Bivi ne poocha kya hua, toh kuch nahi bola. Usko kya bataun ki mere andar kuch toot gaya hai. Job gayi 2 mahine pehle, ab interview bhi nahi aa rahe. Bacche school ke fees ka tension, ghar ka kharcha, sab kuch mere sar par hai. Maine socha tha ki therapy try karun, lekin ek session ka 1500 rupaye lagta hai. Kaise de sakta hoon? Ab bas ghar mein baitha rehta hoon. Kabhi kabhi aisa lagta hai ki sab khatam kar doon. Lekin bivi ka sahara hai, uski wajah se aaj bhi zinda hoon. Par ek baat hai - jab woh kaam par jaati hai, toh mujhe aur bhi bura lagta hai. Mard hokar bhi main ghar mein hu aur woh bahar. Bhai log, koi aisa treatment ya free counseling bataye jo affordable ho? Aur yeh bataye ki is situation mein apne bacchon ko kaise face karun? Unke saamne toh main strong rehna chahta hoon.

Thyroid Thandi Hai? 5 Desi Nuskhe for Energy & Weight Loss

If you feel like you’re dragging yourself through the day despite getting 8 hours of sleep, or if your weight refuses to budge no matter how much you exercise, you might be dealing with more than just a busy lifestyle. As an Indian doctor, I see countless patients—especially women in their 30s and 40s—who come to me saying, “Doctor, I feel so tired all the time, and I’m gaining weight without any reason.” Often, the culprit is an underactive thyroid, or hypothyroidism. Let’s understand why this happens and, more importantly, how you can boost your energy and metabolism naturally. Why Hypothyroidism Drains Your Energy Your thyroid gland, located in your neck, acts like the body’s accelerator. It produces hormones (T3 and T4) that control your metabolism—how fast your body burns calories and produces energy. When your thyroid is sluggish, your metabolism slows down. This is why you feel extreme fatigue, brain fog, and even muscle weakness. Common symptoms in Indians include: Feeling tired even after a full night’s sleep Unexplained weight gain, especially around the belly Dry skin, hair fall, and brittle nails Constipation and feeling cold all the time Heavy or irregular periods in women Home Remedies and Diet Tips to Boost Energy The good news is that with the right lifestyle changes, you can manage hypothyroidism and feel more energetic. Here are actionable, Indian-friendly tips: 1. Eat Thyroid-Friendly Foods Include selenium-rich foods: Selenium helps convert T4 to the active T3 hormone. Eat 2-3 Brazil nuts daily, or enjoy mushrooms, sunflower seeds, and eggs. Zinc is your friend: Zinc supports thyroid function. Add pumpkin seeds, chickpeas (chana), and cashews to your diet. Eat iodine in moderation: Use iodized salt, but don’t overdo it. Include seaweed, fish, or milk in small amounts. Go for complex carbs: Swap white rice for brown rice, quinoa, or millets (bajra, jowar) to avoid blood sugar crashes that worsen fatigue. 2. Avoid These Foods Goitrogens in excess: Raw cruciferous veggies like cabbage, cauliflower, and broccoli can interfere with thyroid function if eaten raw in large amounts. Cook them well before eating. Soy products: Limit tofu, soya chunks, and soy milk, as they can affect hormone absorption. Processed foods and sugar: These spike insulin and worsen inflammation, making fatigue worse. 3. Simple Lifestyle Changes Take your thyroid medication correctly: Always take it on an empty stomach, 30-60 minutes before breakfast, with plain water. Avoid coffee, tea, or calcium-rich foods for at least an hour. Move your body gently: Start with 15-20 minutes of brisk walking or yoga. Poses like Shoulder Stand (Sarvangasana) and Fish Pose (Matsyasana) stimulate the thyroid. Manage stress: Chronic stress raises cortisol, which can suppress thyroid function. Practice deep breathing or 5 minutes of meditation daily. Sleep like it matters: Aim for 7-8 hours of quality sleep. Avoid screens 30 minutes before bed. When to See a Doctor While home remedies help, hypothyroidism is a medical condition that often requires treatment. Please see a doctor if: Your fatigue is persistent and interfering with daily life You have symptoms like severe hair loss, depression, or irregular heartbeats You are pregnant or planning a pregnancy (uncontrolled thyroid can affect the baby) Your TSH levels are above 4.5 mIU/L or as advised by your doctor Your doctor will likely prescribe levothyroxine—a safe, effective medication that replaces the missing thyroid hormone. Don’t stop it without consulting your doctor, even if you feel better. Remember, you are not lazy or weak. Hypothyroidism is a real medical condition, and with the right treatment, diet, and self-care, you can reclaim your energy. Listen to your body, and don’t hesitate to seek help. You deserve to feel vibrant and healthy again.

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