anafast th 4mg/100mg/325mg tablet allopathy (Thiocolchicoside (4mg) + Aceclofenac (100mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
anafast th 4mg/100mg/325mg tablet allopathy (Thiocolchicoside (4mg) + Aceclofenac (100mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Overseas Healthcare Pvt Ltd. Contains Thiocolchicoside (4mg) + Aceclofenac (100mg).

anafast th 4mg/100mg/325mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 Overseas Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is anafast th 4mg/100mg/325mg tablet used for?

Anaflam TH 4 Tablet (Thiocolchicoside + Aceclofenac) is used to treat Acute musculoskeletal pain. It contains Thiocolchicoside (4mg) + Aceclofenac (100mg), which Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxat. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Thiocolchicoside + Aceclofenac
  • Manufacturer: Overseas Healthcare Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 anafast th 4mg/100mg/325mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

anafast th 4mg/100mg/325mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Thiocolchicoside (4mg) + Aceclofenac (100mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Thiocolchicoside + Aceclofenac
Brand NameAnaflam TH 4 Tablet
ManufacturerOverseas Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassMuscle Relaxant + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed in body tissues
Protein BindingThiocolchicoside: ~13%; Aceclofenac: >99%
MetabolismThiocolchicoside: Hepatic; Aceclofenac: Hepatic via CYP2C9
Half-LifeThiocolchicoside: ~7 hours; Aceclofenac: ~4 hours
ExcretionThiocolchicoside: Renal (70-80%); Aceclofenac: Renal (70-80%)
BioavailabilityThiocolchicoside: ~25%; Aceclofenac: ~100%
Onset of ActionThiocolchicoside: 30-60 min; Aceclofenac: 30 min
Peak Plasma TimeThiocolchicoside: 1-2 hours; Aceclofenac: 1-3 hours
Duration of ActionThiocolchicoside: 4-6 hours; Aceclofenac: 12-24 hours

Pharmacodynamics

Mechanism of ActionThiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis
Target ReceptorThiocolchicoside: GABA-A receptor, glycine receptor; Aceclofenac: COX-1, COX-2
Pharmacodynamic EffectsMuscle relaxation, analgesia, anti-inflammatory

💡 How and when to take anafast th 4mg/100mg/325mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture

⚙️ How anafast th 4mg/100mg/325mg tablet Works

Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis

1 Thiocolchicoside binds to GABA-A receptors, enhancing inhibitory neurotransmission
⬇️
2 Thiocolchicoside also acts on glycine receptors, promoting spinal inhibition
⬇️
3 Aceclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes
⬇️
4 Inhibition of COX reduces conversion of arachidonic acid to prostaglandins
⬇️
5 Decreased prostaglandins lead to reduced pain and inflammation

💊 anafast th 4mg/100mg/325mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Acute musculoskeletal pain, muscle spasms, inflammatory conditions

Off-label uses: Not well established

⚠️ What are the side effects of anafast th 4mg/100mg/325mg tablet?

✅ Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Somnolence

🚨 Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Stevens-Johnson syndrome
  • Seizures

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulceration risk
Other NSAIDs Major Additive GI and renal toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect, increased nephrotoxicity
Anticoagulants Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulceration risk
Antacids Minor Reduced absorption of aceclofenac
Digoxin Minor Possible increased digoxin levels
Phenytoin Minor Possible increased phenytoin levels

🚨 Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Aspirin
  • Other NSAIDs

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

ℹ️ Minor Interactions

  • Antacids
  • Digoxin
  • Phenytoin

🍽️ Food Interactions

May be taken with food to reduce GI upset

🍷 Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, pregnancy (third trimester), lactation, children <16 years

📊 Monitoring Parameters

Liver function, renal function, blood pressure, GI symptoms

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

🛑 Myths vs. Facts about anafast th 4mg/100mg/325mg tablet

  • Myth: Generic substitutes of anafast th 4mg/100mg/325mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Thiocolchicoside (4mg) + Aceclofenac (100mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of anafast th 4mg/100mg/325mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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