amrub l 75mg/20mg capsule - Uses, Price, Side Effects & Substitutes
What is amrub l 75mg/20mg capsule used for?
Acera-L Capsule SR (Levosulpiride + Rabeprazole) is used to treat Gastroesophageal reflux disease (GERD); dyspepsia; gastroparesis; irritable bowel syndrome with constipation. It contains Levosulpiride (75mg) + Rabeprazole (20mg), which Levosulpiride: Dopamine D2 receptor antagonist in GI tract, enhancing motility; . Always consult your doctor before use. Take as prescribed.
- Generic Name: Levosulpiride + Rabeprazole
- Manufacturer: Amble Biotech Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 amrub l 75mg/20mg capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)
amrub l 75mg/20mg capsule का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Levosulpiride (75mg) + Rabeprazole (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Levosulpiride + Rabeprazole |
|---|---|
| Brand Name | Acera-L Capsule SR |
| Manufacturer | Amble Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral (sustained release capsule) |
| Storage | Store at room temperature (20-25°C); protect from moisture and light |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take amrub l 75mg/20mg capsule?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C); protect from moisture and light
⚙️ How amrub l 75mg/20mg capsule Works
Levosulpiride: Dopamine D2 receptor antagonist in GI tract, enhancing motility; Rabeprazole: Irreversible inhibition of H+/K+ ATPase in gastric parietal cells, reducing acid secretion
💊 amrub l 75mg/20mg capsule Uses in Hindi (Ke Fayde), Benefits & Indications
Gastroesophageal reflux disease (GERD); dyspepsia; gastroparesis; irritable bowel syndrome with constipation
Off-label uses: Diabetic gastroparesis; functional dyspepsia; cyclic vomiting syndrome
⚠️ What are the side effects of amrub l 75mg/20mg capsule?
✅ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Dizziness
- Constipation
🚨 Serious Side Effects
- QT prolongation
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- Clostridium difficile infection
- Fractures (long-term)
⚠️ Rare Side Effects
- Gynecomastia
- Galactorrhea
- Interstitial nephritis
- Lupus erythematosus
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Clopidogrel | Major | Reduced antiplatelet effect |
| Methotrexate | Major | Increased methotrexate toxicity |
| Cilostazol | Major | Increased cilostazol levels |
| Atazanavir | Major | Reduced atazanavir absorption |
| Diazepam | Moderate | Increased diazepam levels |
| Phenytoin | Moderate | Increased phenytoin levels |
| Digoxin | Moderate | Increased digoxin levels |
| Ketoconazole | Moderate | Reduced ketoconazole absorption |
| Iron salts | Moderate | Reduced iron absorption |
| Sucralfate | Minor | Reduced absorption of levosulpiride |
| Antacids | Minor | Reduced absorption of rabeprazole |
| Vitamin B12 | Minor | Reduced B12 absorption with long-term use |
🚨 Major Interactions
- Warfarin
- Clopidogrel
- Methotrexate
- Cilostazol
- Atazanavir
⚡ Moderate Interactions
- Diazepam
- Phenytoin
- Digoxin
- Ketoconazole
- Iron salts
ℹ️ Minor Interactions
- Sucralfate
- Antacids
- Vitamin B12
🍽️ Food Interactions
Food may delay absorption of both components; avoid high-fat meals
🍷 Alcohol Interaction
Avoid alcohol; may increase risk of GI side effects
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to components; GI hemorrhage; mechanical obstruction; perforation; pheochromocytoma; concomitant use with neuroleptics
📊 Monitoring Parameters
Liver function tests; renal function; ECG (QT interval); serum electrolytes; magnesium levels
🤱 Lactation Safety
Excreted in breast milk; use with caution
💊 Overdose Management
Supportive care; activated charcoal; monitor ECG for QT prolongation
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose
🛑 Myths vs. Facts about amrub l 75mg/20mg capsule
- Myth: Generic substitutes of amrub l 75mg/20mg capsule are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Levosulpiride (75mg) + Rabeprazole (20mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amrub l 75mg/20mg capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
💬 Real Patient Experiences (Astitva)
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