Amrizol-DSR Capsule - Uses, Price, Side Effects
What is amrizol-dsr capsule used for?
Amrizol-DSR Capsule is a combination medicine used to treat gastroesophageal reflux disease (GERD) and dyspepsia. It contains Domperidone, which helps control nausea and vomiting by blocking dopamine receptors, and Esomeprazole, a proton pump inhibitor that reduces stomach acid production. Together, they relieve heartburn, acid regurgitation, and stomach discomfort.
- Generic Name: Domperidone + Esomeprazole
- Manufacturer: Nuorik Healthcare
- Medicine Form: Allopathy
- Pregnancy Category: C
🇮🇳 amrizol-dsr capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)
amrizol-dsr capsule का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Domperidone (30mg) + Esomeprazole (40mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Domperidone + Esomeprazole |
|---|---|
| Brand Name | Amrizol-DSR Capsule |
| Manufacturer | Nuorik Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25°C, protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
📅 When to take amrizol-dsr capsule?
💡 How and when to take amrizol-dsr capsule?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C, protect from light and moisture.
⚙️ How amrizol-dsr capsule Works
Domperidone: Blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, enhancing gastric motility and emptying. Esomeprazole: Irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing gastric acid secretion.
💊 amrizol-dsr capsule Uses in Hindi (Ke Fayde), Benefits & Indications
⚠️ What are the side effects of amrizol-dsr capsule?
✅ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Dry mouth
🚨 Serious Side Effects
- QT prolongation
- Torsades de pointes
- Gynecomastia
- Hyperprolactinemia
- Clostridium difficile infection
⚠️ Rare Side Effects
- Jaundice
- Interstitial nephritis
- Anaphylaxis
- Extrapyramidal symptoms
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Moderate | Increased risk of QT prolongation |
| Warfarin | Moderate | Altered anticoagulant effect |
| Cilostazol | Minor | Increased cilostazol levels |
🚨 Major Interactions
- Ketoconazole
- Erythromycin
- Clarithromycin
- Ritonavir
- Amiodarone
⚡ Moderate Interactions
- Cimetidine
- Fluconazole
- Voriconazole
- Diltiazem
- Verapamil
ℹ️ Minor Interactions
- Sucralfate
- Antacids
- Digoxin
🍽️ Food Interactions
Food may delay absorption of domperidone; esomeprazole should be taken before meals for optimal effect.
🍷 Alcohol Interaction
Alcohol may increase gastric irritation and reduce drug efficacy.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, gastrointestinal hemorrhage, mechanical obstruction, perforation, prolactinoma, concurrent use with QT-prolonging drugs.
📊 Monitoring Parameters
ECG for QT interval, renal function, hepatic function, serum electrolytes.
🤱 Lactation Safety
Domperidone is excreted in breast milk; esomeprazole is likely excreted. Use with caution.
💊 Overdose Management
Supportive care, ECG monitoring, activated charcoal if recent ingestion.
⏰ Missed Dose
Take as soon as remembered; skip if almost time for next dose. Do not double dose.
🛑 Myths vs. Facts about amrizol-dsr capsule
- Myth: Generic substitutes of amrizol-dsr capsule are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Domperidone (30mg) + Esomeprazole (40mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amrizol-dsr capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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