Amlopres-NB 5mg/5mg Tablet - Uses, Price, Side Effects
What is amlopres-nb 5mg/5mg tablet used for?
Amlopres-NB 5mg/5mg Tablet is a combination of Nebivolol (a beta-blocker) and Amlodipine (a calcium channel blocker) used to treat hypertension. Nebivolol reduces heart rate and cardiac output, while Amlodipine relaxes blood vessels, lowering blood pressure and reducing the risk of stroke and heart attack.
- Generic Name: Nebivolol + Amlodipine
- Manufacturer: Cipla Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 amlopres-nb 5mg/5mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
amlopres-nb 5mg/5mg tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Nebivolol (5mg) + Amlodipine (5mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Nebivolol + Amlodipine |
|---|---|
| Brand Name | Amlovas SN 5 mg/2.5 mg Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Beta-blocker + Calcium channel blocker) |
| Route of Administration | Oral |
| Storage | Store at 20-25°C (68-77°F); protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
📅 When to take amlopres-nb 5mg/5mg tablet?
💡 How and when to take amlopres-nb 5mg/5mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F); protect from light and moisture.
⚙️ How amlopres-nb 5mg/5mg tablet Works
Nebivolol: Selective beta-1 adrenergic receptor blocker with nitric oxide-mediated vasodilation; Amlodipine: Dihydropyridine calcium channel blocker inhibiting calcium influx into vascular smooth muscle and cardiac muscle.
💊 amlopres-nb 5mg/5mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Hypertension (first-line or add-on therapy).
Off-label uses: Chronic stable angina, heart failure (nebivolol only).
⚠️ What are the side effects of amlopres-nb 5mg/5mg tablet?
✅ Common Side Effects
- Headache
- Dizziness
- Fatigue
- Edema
- Nausea
- Bradycardia
🚨 Serious Side Effects
- Heart block
- Severe hypotension
- Bronchospasm
- Hepatotoxicity
⚠️ Rare Side Effects
- Thrombocytopenia
- Stevens-Johnson syndrome
- Gingival hyperplasia
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| CYP3A4 inhibitors (e.g., ketoconazole) | Moderate | Increased amlodipine levels |
| Beta-blockers (e.g., metoprolol) | Moderate | Additive bradycardia |
🚨 Major Interactions
- CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Other antihypertensives (additive hypotension)
- Beta-blockers (additive bradycardia)
⚡ Moderate Interactions
- NSAIDs (reduced antihypertensive effect)
- Digoxin (increased bradycardia)
- Cimetidine (increased nebivolol levels)
ℹ️ Minor Interactions
- Grapefruit juice (increased amlodipine levels)
- Alcohol (enhanced hypotensive effect)
🍽️ Food Interactions
Grapefruit juice may increase amlodipine levels; avoid excessive intake.
🍷 Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, severe bradycardia, heart block, cardiogenic shock, sick sinus syndrome, severe hypotension, decompensated heart failure.
📊 Monitoring Parameters
Blood pressure, heart rate, ECG, renal function, hepatic function.
🤱 Lactation Safety
Not recommended; both drugs excreted in breast milk.
💊 Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for calcium channel blocker overdose.
⏰ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose.
🛑 Myths vs. Facts about amlopres-nb 5mg/5mg tablet
- Myth: Generic substitutes of amlopres-nb 5mg/5mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Nebivolol (5mg) + Amlodipine (5mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of amlopres-nb 5mg/5mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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