Amidine 5 Tablet - Uses, Price, Side Effects
What is amidine 5 tablet used for?
Amidine 5 Tablet contains Amlodipine 5mg, a calcium channel blocker used to treat high blood pressure and chest pain (angina). It works by relaxing blood vessels, making it easier for the heart to pump blood. This helps lower blood pressure and reduce the frequency of angina attacks.
- Generic Name: Amlodipine
- Manufacturer: Iatric Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ amidine 5 tablet Uses & Benefits
Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina).
Off-label uses: Raynaud's phenomenon, migraine prophylaxis, high-altitude pulmonary edema.
๐ Drug Information
| Generic Name(s) | Amlodipine |
| Brand Name | Amlokind 5 Tablet |
| Manufacturer | Iatric Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Dihydropyridines (DHP) |
| Route of Administration | Oral. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.
Mechanism Steps
๐ก How to Take amidine 5 tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of amidine 5 tablet
โ Common Side Effects
- Edema (peripheral)
- Dizziness
- Flushing
- Palpitations
- Fatigue
- Nausea
๐จ Serious Side Effects
- Severe hypotension
- Myocardial infarction (rare)
- Hepatotoxicity (rare)
- Stevens-Johnson syndrome (rare)
โ ๏ธ Rare Side Effects
- Gingival hyperplasia
- Gynecomastia
- Leukopenia
- Vasculitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Grapefruit juice | Moderate | Increased amlodipine concentration |
| Simvastatin | Moderate | Increased simvastatin levels, risk of myopathy |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Simvastatin
โก Moderate Interactions
- Grapefruit juice
- Diltiazem
- Clarithromycin
โน๏ธ Minor Interactions
- Antacids
- Sildenafil
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase amlodipine levels.
๐ท Alcohol Interaction
Alcohol may potentiate the hypotensive effect.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amlodipine or dihydropyridines, severe hypotension, cardiogenic shock.
๐ Monitoring Parameters
Blood pressure, heart rate, peripheral edema, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; calcium gluconate may be beneficial.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for amidine 5 tablet
View AllAlternative brands with exact same active ingredient (Amlodipine (5mg)):
-
amlodepin 5mg tabletBiochem Pharmaceutical Industries โน4.56 79.7% CHEAPER
-
davaindia amlodipine 5mg tabletDavaindia Generic Pharmacy โน5.63 75% CHEAPER
-
amoline 5mg tabletZeelab Pharmacy Pvt Ltd โน6.00 73.3% CHEAPER
-
mlo 5mg tabletWest-Coast Pharmaceutical Works Ltd โน6.00 73.3% CHEAPER
-
s-amoline 5 tabletZeelab Pharmacy Pvt Ltd โน6.00 73.3% CHEAPER
-
StayHappi Amlodipine 5mg TabletSarvagunaushdhi Pvt Ltd โน7.00 68.9% CHEAPER
-
elpress 5mg tabletElder Pharmaceuticals Ltd โน7.43 67% CHEAPER
-
udp 5 tabletUnison Pharmaceuticals Pvt Ltd โน7.47 66.8% CHEAPER
-
angiguard 5mg tabletInd Swift Laboratories Ltd โน7.50 66.7% CHEAPER
-
amlica 5mg tabletCadex Laboratories โน8.44 62.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.