alzolam 0.125mg tablet - Alprazolam (0.125mg) medicine

Alzolam 0.125mg Tablet - Uses, Price, Side Effects

No reviews yet
๐Ÿญ Sun Pharmaceutical Industries Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is alzolam 0.125mg tablet used for?

Alzolam 0.125mg Tablet contains Alprazolam, a benzodiazepine used to treat anxiety and panic disorders. It works by enhancing the effect of GABA, a natural chemical in the brain that promotes calmness and reduces excessive nerve activity. This helps relieve symptoms of anxiety, tension, and panic attacks.

  • Generic Name: Alprazolam
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š alzolam 0.125mg tablet Uses & Benefits

Generalized anxiety disorder (GAD), Panic disorder with or without agoraphobia, Short-term relief of anxiety symptoms

Off-label uses: Insomnia (short-term), Premenstrual dysphoric disorder (PMDD), Cataplexy associated with narcolepsy

๐Ÿ“‹ Drug Information

Generic Name(s)Alprazolam
Brand NameAlprax 0.25 Tablet
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepines
Route of AdministrationOral
StorageStore at 20โ€“25ยฐC (68โ€“77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract with oral bioavailability of approximately 90%.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.
Protein Binding80% bound to plasma proteins, primarily albumin.
MetabolismExtensively metabolized in the liver via CYP3A4 to active metabolites (e.g., alpha-hydroxyalprazolam).
Half-LifeMean elimination half-life is 11.2 hours (range 6.3โ€“26.9 hours).
ExcretionPrimarily excreted in urine as metabolites (80%) and feces (7%).
Bioavailability90%
Onset of ActionRapid onset within 15โ€“30 minutes.
Peak Plasma Time1โ€“2 hours after oral administration.
Duration of Action4โ€“6 hours for immediate-release formulations.

How It Works

Enhances the inhibitory effect of gamma-aminobutyric acid (GABA) at GABA-A receptors, increasing chloride ion influx and neuronal hyperpolarization.

Mechanism Steps

1Alprazolam binds to the benzodiazepine site on GABA-A receptors.
2Binding enhances the affinity of GABA for the receptor.
3Increased GABA binding leads to more frequent opening of chloride ion channels.

๐Ÿ’ก How to Take alzolam 0.125mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alzolam 0.125mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Ataxia
  • Slurred speech
  • Memory impairment

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Paradoxical reactions (e.g., agitation, aggression)
  • Physical dependence and withdrawal syndrome
  • Seizures (with abrupt discontinuation)

โš ๏ธ Rare Side Effects

  • Jaundice
  • Blood dyscrasias (e.g., agranulocytosis)
  • Anaphylaxis
  • Angle-closure glaucoma

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Increased CNS depression and sedation
Opioid analgesics Major Additive CNS depression, respiratory depression
Ketoconazole Moderate Increased alprazolam concentration

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir) โ€“ increased alprazolam levels
  • CYP3A4 inducers (e.g., carbamazepine, rifampin) โ€“ decreased alprazolam levels
  • Opioids (e.g., morphine, oxycodone) โ€“ additive CNS depression, risk of respiratory depression
  • Other benzodiazepines โ€“ additive sedation

โšก Moderate Interactions

  • Alcohol โ€“ additive CNS depression
  • Antidepressants (e.g., SSRIs, MAOIs) โ€“ potential for increased sedation
  • Antipsychotics โ€“ additive sedation
  • Muscle relaxants โ€“ enhanced muscle relaxation

โ„น๏ธ Minor Interactions

  • Oral contraceptives โ€“ may increase alprazolam levels
  • Cimetidine โ€“ increased alprazolam levels
  • Grapefruit juice โ€“ increased alprazolam levels

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase alprazolam levels; food delays absorption but does not significantly affect bioavailability.

๐Ÿท Alcohol Interaction

Severe additive CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category D

๐Ÿšซ Contraindications

Hypersensitivity to alprazolam or other benzodiazepines, Acute narrow-angle glaucoma, Severe respiratory insufficiency, Myasthenia gravis, Concurrent use with opioids (except in monitored settings)

๐Ÿ“Š Monitoring Parameters

CNS depression (sedation, dizziness), Respiratory rate, Blood pressure, Liver function tests (LFTs), Renal function tests (RFTs), Complete blood count (CBC) with long-term use

๐Ÿคฑ Lactation Safety

Low risk; alprazolam is excreted in breast milk; monitor infant for sedation and feeding difficulties.

๐Ÿ’Š Overdose Management

Supportive care; flumazenil (benzodiazepine antagonist) may be used but with caution due to risk of seizures.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; skip missed dose if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for alzolam 0.125mg tablet

View All

Alternative brands with exact same active ingredient (Alprazolam (0.125mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install