alpan 20mg tablet - Pantoprazole (20mg) medicine

alpan 20mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Altak Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is alpan 20mg tablet used for?

Aciban 40 Tablet (Pantoprazole) is used to treat GASTRO INTESTINAL. It contains Pantoprazole (20mg), which Proton pump inhibitor that irreversibly inhibits H+/K+ ATPase in gastric parieta. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Pantoprazole
  • Manufacturer: Altak Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š alpan 20mg tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (combination therapy), peptic ulcer disease.

Off-label uses: Stress ulcer prophylaxis in critically ill patients; prevention of NSAID-induced ulcers.

๐Ÿ“‹ Drug Information

Generic Name(s)Pantoprazole
Brand NameAciban 40 Tablet
ManufacturerAltak Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; absorption is rapid and complete.
DistributionVolume of distribution about 0.15 L/kg; extensively distributed in tissues.
Protein BindingApproximately 98% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes.
Half-LifeAbout 1 hour (range 0.5-1.5 hours) in healthy subjects; prolonged in hepatic impairment.
ExcretionPrimarily renal (about 80% as metabolites); remainder in feces.
BioavailabilityOral bioavailability about 77%.
Onset of ActionWithin 1 hour; maximal acid suppression occurs after 2-4 days of dosing.
Peak Plasma Time2-3 hours after oral administration.
Duration of ActionAcid suppression lasts up to 24 hours after a single dose.

How It Works

Proton pump inhibitor that irreversibly inhibits H+/K+ ATPase in gastric parietal cells.

Mechanism Steps

1Pantoprazole is a prodrug that accumulates in the acidic environment of gastric parietal cell canaliculi.
2It is protonated and converted to its active form, a sulfenamide.
3The active form binds covalently to cysteine residues of the H+/K+ ATPase enzyme.

๐Ÿ’ก How to Take alpan 20mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alpan 20mg tablet

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Constipation

๐Ÿšจ Serious Side Effects

  • Clostridium difficile-associated diarrhea
  • Fractures (hip, wrist, spine) with long-term use
  • Hypomagnesemia
  • Vitamin B12 deficiency
  • Acute interstitial nephritis
  • Cutaneous lupus erythematosus

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Pancreatitis
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Clopidogrel Major Reduced antiplatelet effect due to CYP2C19 inhibition
Methotrexate Major Increased methotrexate toxicity
Atazanavir Major Reduced atazanavir absorption
Rilpivirine Major Reduced rilpivirine absorption
Cilostazol Major Increased cilostazol levels
Warfarin Moderate Increased INR and bleeding risk
Phenytoin Moderate Increased phenytoin levels
Diazepam Moderate Increased diazepam levels
Digoxin Moderate Possible increased digoxin levels
Iron salts Moderate Reduced iron absorption
Mycophenolate mofetil Moderate Reduced mycophenolate absorption
Ketoconazole Minor Reduced ketoconazole absorption
Itraconazole Minor Reduced itraconazole absorption
Ampicillin esters Minor Reduced ampicillin absorption
Sucralfate Minor Reduced pantoprazole absorption

๐Ÿšจ Major Interactions

  • Clopidogrel
  • Methotrexate
  • Atazanavir
  • Rilpivirine
  • Cilostazol

โšก Moderate Interactions

  • Warfarin
  • Phenytoin
  • Diazepam
  • Digoxin
  • Iron salts
  • Mycophenolate mofetil

โ„น๏ธ Minor Interactions

  • Ketoconazole
  • Itraconazole
  • Ampicillin esters
  • Sucralfate

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not affect extent; best taken before meals.

๐Ÿท Alcohol Interaction

No direct interaction; alcohol may aggravate gastric conditions.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to pantoprazole or any component; co-administration with rilpivirine.

๐Ÿ“Š Monitoring Parameters

Symptoms of acid-related disorders; magnesium levels with prolonged use; bone density with long-term use.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote; hemodialysis not effective.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for alpan 20mg tablet

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Alternative brands with exact same active ingredient (Pantoprazole (20mg)):

Medical Note: Always consult your doctor before switching medications.

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