alpa 650mg tablet - Paracetamol (650mg) medicine

Alpa 650mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Alpic Biotech Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is alpa 650mg tablet used for?

Alpa 650mg Tablet contains Paracetamol, a pain reliever and fever reducer. It works by blocking the production of certain chemicals in the brain that cause pain and fever. It is used for mild to moderate pain such as headache, toothache, and menstrual cramps, as well as to reduce fever.

  • Generic Name: Paracetamol
  • Manufacturer: Alpic Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š alpa 650mg tablet Uses & Benefits

Mild to moderate pain (headache, dental pain, dysmenorrhea, osteoarthritis); fever.

Off-label uses: Patent ductus arteriosus closure in neonates (IV form); osteoarthritis pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Paracetamol
Brand NameAction or 1000mg Tablet
ManufacturerAlpic Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAnalgesic & Antipyretic-PCM
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionWidely distributed throughout body fluids; crosses placenta and appears in breast milk.
Protein Binding10-25%
MetabolismHepatic via conjugation (glucuronidation and sulfation); minor oxidation via CYP2E1.
Half-Life1.5-3 hours
ExcretionRenal (90-100% as metabolites within 24 hours).
Bioavailability75-85%
Onset of Action30-60 minutes
Peak Plasma Time30-60 minutes
Duration of Action4-6 hours

How It Works

Inhibits cyclooxygenase (COX) in the central nervous system, reducing prostaglandin synthesis; also activates descending serotonergic pathways.

Mechanism Steps

1Inhibition of COX-1 and COX-2 in the central nervous system
2Reduction of prostaglandin synthesis in the hypothalamus
3Activation of descending serotonergic pathways

๐Ÿ’ก How to Take alpa 650mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alpa 650mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Constipation
  • Rash

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Acute liver failure
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Acute generalized exanthematous pustulosis

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Leukopenia
  • Neutropenia
  • Pancreatitis
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Alcohol Moderate Increased risk of liver toxicity
Isoniazid Moderate Increased risk of hepatotoxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Alcohol (chronic heavy use)
  • Isoniazid
  • Rifampin
  • Carbamazepine
  • Phenytoin
  • Barbiturates

โšก Moderate Interactions

  • Cholestyramine
  • Metoclopramide
  • Domperidone
  • Probenecid
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Caffeine
  • Zidovudine
  • Lamotrigine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; high-fat meals reduce peak concentration.

๐Ÿท Alcohol Interaction

Chronic heavy alcohol use increases hepatotoxicity risk; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to paracetamol; severe hepatic impairment; chronic alcoholism.

๐Ÿ“Š Monitoring Parameters

Liver function tests (in overdose or chronic high doses); renal function in long-term use.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; considered safe at therapeutic doses.

๐Ÿ’Š Overdose Management

Activated charcoal if within 1 hour; N-acetylcysteine (NAC) as antidote; monitor liver function.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for alpa 650mg tablet

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Alternative brands with exact same active ingredient (Paracetamol (650mg)):

Medical Note: Always consult your doctor before switching medications.

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