alofen m 10mg/120mg tablet - Uses, Price, Side Effects & Substitutes
What is alofen m 10mg/120mg tablet used for?
Air-M Tablet (Montelukast + Fexofenadine) is used to treat Seasonal allergic rhinitis. It contains Montelukast (10mg) + Fexofenadine (120mg), which Montelukast selectively antagonizes leukotriene D4 at the cysteinyl leukotriene . Always consult your doctor before use. Take as prescribed.
- Generic Name: Montelukast + Fexofenadine
- Manufacturer: In Med Therapeutics
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 alofen m 10mg/120mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
alofen m 10mg/120mg tablet का उपयोग मुख्य रूप से respiratory और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Montelukast (10mg) + Fexofenadine (120mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Montelukast + Fexofenadine |
|---|---|
| Brand Name | Air-M Tablet |
| Manufacturer | In Med Therapeutics |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Leukotriene receptor antagonist + Antihistamine |
| Route of Administration | Oral. |
| Storage | Store at 20-25°C (68-77°F), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take alofen m 10mg/120mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F), protect from light and moisture.
⚙️ How alofen m 10mg/120mg tablet Works
Montelukast selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor CysLT1, reducing airway edema, smooth muscle contraction, and inflammatory cell activity. Fexofenadine is a peripherally selective histamine H1 receptor antagonist, inhibiting histamine-mediated allergic responses.
💊 alofen m 10mg/120mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Seasonal allergic rhinitis, perennial allergic rhinitis, asthma prophylaxis, urticaria.
Off-label uses: Exercise-induced bronchoconstriction (montelukast), chronic urticaria.
⚠️ What are the side effects of alofen m 10mg/120mg tablet?
✅ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Fatigue
- Cough
- Pharyngitis
🚨 Serious Side Effects
- Anaphylaxis
- Angioedema
- Severe skin reactions (e.g., eosinophilic granulomatosis with polyangiitis)
- Hepatic dysfunction
⚠️ Rare Side Effects
- Seizures
- Thrombocytopenia
- Hallucinations
- Churg-Strauss syndrome
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased montelukast levels |
| Rifampin | Major | Decreased montelukast efficacy |
| Erythromycin | Moderate | Increased fexofenadine levels |
| Warfarin | Moderate | Possible increased INR |
| Fruit juices | Minor | Reduced fexofenadine absorption |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2C9 inhibitors (e.g., fluconazole)
- Rifampin
- Phenobarbital
⚡ Moderate Interactions
- Erythromycin
- Gemfibrozil
- Warfarin
ℹ️ Minor Interactions
- Theophylline
- Oral contraceptives
🍽️ Food Interactions
Fexofenadine absorption may be reduced by fruit juices (apple, orange, grapefruit). Montelukast absorption not significantly affected by food.
🍷 Alcohol Interaction
Alcohol may potentiate CNS depression; caution advised.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to any component.
📊 Monitoring Parameters
Liver function tests, renal function, asthma control, allergic symptom relief.
🤱 Lactation Safety
Montelukast: excreted in breast milk; Fexofenadine: excreted in breast milk; caution advised.
💊 Overdose Management
Symptomatic and supportive treatment; no specific antidote.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
🛑 Myths vs. Facts about alofen m 10mg/120mg tablet
- Myth: Generic substitutes of alofen m 10mg/120mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Montelukast (10mg) + Fexofenadine (120mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of alofen m 10mg/120mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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