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alfuzosin-d tablet er allopathy (Alfuzosin (10mg) + Dutasteride (0.5mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
alfuzosin-d tablet er allopathy (Alfuzosin (10mg) + Dutasteride (0.5mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Care Formulation Labs Pvt Ltd. Contains Alfuzosin (10mg) + Dutasteride (0.5mg).

alfuzosin-d tablet er - Uses, Price, Side Effects & Substitutes

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🏭 Care Formulation Labs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is alfuzosin-d tablet er used for?

Alfugress-D Tablet SR (Alfuzosin + Dutasteride) is used to treat Benign prostatic hyperplasia (BPH). It contains Alfuzosin (10mg) + Dutasteride (0.5mg), which Alfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: I. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Alfuzosin + Dutasteride
  • Manufacturer: Care Formulation Labs Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 alfuzosin-d tablet er के बारे में संक्षिप्त जानकारी (Hindi Summary)

alfuzosin-d tablet er का उपयोग मुख्य रूप से urology और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Alfuzosin (10mg) + Dutasteride (0.5mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Alfuzosin + Dutasteride
Brand NameAlfugress-D Tablet SR
ManufacturerCare Formulation Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassAlpha-1 adrenergic blocker + 5-alpha-reductase inhibitor
Route of AdministrationOral
StorageStore at 20-25°C, protect from light and moisture
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAlfuzosin: Rapidly absorbed; Dutasteride: Well absorbed
DistributionAlfuzosin: Vd 3.2 L/kg; Dutasteride: Vd 300-500 L
Protein BindingAlfuzosin: 82-90%; Dutasteride: >99%
MetabolismAlfuzosin: Hepatic (CYP3A4); Dutasteride: Hepatic (CYP3A4, CYP3A5)
Half-LifeAlfuzosin: 5-7 hours; Dutasteride: 5 weeks
ExcretionAlfuzosin: 75% feces, 24% urine; Dutasteride: Feces (mainly), urine (<1%)
BioavailabilityAlfuzosin: 49%; Dutasteride: 60%
Onset of ActionAlfuzosin: 1-2 hours; Dutasteride: 2 weeks
Peak Plasma TimeAlfuzosin: 8 hours (ER); Dutasteride: 2-3 hours
Duration of ActionAlfuzosin: 24 hours; Dutasteride: 24 hours (steady state months)

Pharmacodynamics

Mechanism of ActionAlfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: Inhibits 5-alpha-reductase, reducing DHT
Target ReceptorAlfuzosin: Alpha-1 adrenoceptor; Dutasteride: 5-alpha-reductase type 1 and 2
Pharmacodynamic EffectsRelaxation of smooth muscle in prostate/urethra; Reduction of prostate volume

💡 How and when to take alfuzosin-d tablet er?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C, protect from light and moisture

⚙️ How alfuzosin-d tablet er Works

Alfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: Inhibits 5-alpha-reductase, reducing DHT

1 Alfuzosin binds to alpha-1 adrenoceptors in prostate and bladder neck smooth muscle
⬇️
2 Blocks norepinephrine binding, causing smooth muscle relaxation
⬇️
3 Reduces urethral resistance and improves urine flow
⬇️
4 Dutasteride inhibits 5-alpha-reductase types 1 and 2
⬇️
5 Prevents conversion of testosterone to dihydrotestosterone (DHT)
⬇️
6 Reduces DHT levels in prostate, leading to decreased prostate volume
⬇️
7 Combined effect relieves BPH symptoms and reduces risk of acute urinary retention

💊 alfuzosin-d tablet er Uses in Hindi (Ke Fayde), Benefits & Indications

Benign prostatic hyperplasia (BPH)

Off-label uses: Male pattern baldness (dutasteride alone)

⚠️ What are the side effects of alfuzosin-d tablet er?

✅ Common Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Nasopharyngitis
  • Decreased libido
  • Erectile dysfunction
  • Ejaculation disorders

🚨 Serious Side Effects

  • Orthostatic hypotension
  • Syncope
  • Priapism
  • Breast cancer (rare)

⚠️ Rare Side Effects

  • Angioedema
  • Hepatotoxicity
  • Depression

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Ketoconazole Major Increased alfuzosin/dutasteride levels
Warfarin Moderate Increased INR
Cimetidine Moderate Increased dutasteride levels

🚨 Major Interactions

  • CYP3A4 inhibitors (ketoconazole, ritonavir)
  • Other alpha-blockers
  • Antihypertensives

⚡ Moderate Interactions

  • Cimetidine
  • Warfarin
  • CYP3A4 inducers

ℹ️ Minor Interactions

  • Digoxin
  • Theophylline

🍽️ Food Interactions

Alfuzosin: Food increases absorption; Dutasteride: No significant effect

🍷 Alcohol Interaction

May increase hypotension risk

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, severe hepatic impairment, orthostatic hypotension, women/children

📊 Monitoring Parameters

Blood pressure, prostate-specific antigen (PSA), liver function

🤱 Lactation Safety

Not recommended; Dutasteride excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; hypotension treatment

⏰ Missed Dose

Take as soon as remembered; skip if near next dose

🛑 Myths vs. Facts about alfuzosin-d tablet er

  • Myth: Generic substitutes of alfuzosin-d tablet er are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Alfuzosin (10mg) + Dutasteride (0.5mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of alfuzosin-d tablet er can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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