alerflo nasal spray - Fluticasone Propionate (27.5mcg) medicine

alerflo nasal spray - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Dr Reddy's Laboratories Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is alerflo nasal spray used for?

Alerflo Nasal Spray (Fluticasone Propionate) is used to treat RESPIRATORY. It contains Fluticasone Propionate (27.5mcg), which Binds to glucocorticoid receptors, leading to anti-inflammatory effects.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Fluticasone Propionate
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š alerflo nasal spray Uses & Benefits

Allergic rhinitis (seasonal and perennial), non-allergic rhinitis.

Off-label uses: Nasal polyps, chronic sinusitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Fluticasone Propionate
Brand NameAlerflo Nasal Spray
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassGlucocorticoids
Route of AdministrationIntranasal
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed primarily in the nasal mucosa; systemic absorption is low due to extensive first-pass metabolism.
DistributionVolume of distribution is approximately 4.2 L/kg; highly protein bound.
Protein BindingApproximately 91%
MetabolismMetabolized by cytochrome P450 3A4 (CYP3A4) to inactive metabolites.
Half-LifeApproximately 7.8 hours
ExcretionExcreted primarily in feces (as metabolites) and to a lesser extent in urine.
BioavailabilityLess than 2% systemically due to extensive first-pass metabolism.
Onset of ActionWithin 12 hours; maximal benefit may take several days.
Peak Plasma TimeNot applicable due to low systemic absorption; local effect.
Duration of Action24 hours with once-daily dosing.

How It Works

Binds to glucocorticoid receptors, leading to anti-inflammatory effects.

Mechanism Steps

1Fluticasone propionate binds to glucocorticoid receptors in nasal mucosa.
2Receptor-ligand complex translocates to nucleus.
3Complex binds to glucocorticoid response elements (GREs) on DNA.

๐Ÿ’ก How to Take alerflo nasal spray

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alerflo nasal spray

โœ… Common Side Effects

  • Nasal irritation
  • Headache
  • Epistaxis
  • Pharyngitis

๐Ÿšจ Serious Side Effects

  • Adrenal suppression
  • Glaucoma
  • Cataracts
  • Nasal septal perforation

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Angioedema
  • Bronchospasm

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased fluticasone levels, risk of systemic effects
Ritonavir Major Increased fluticasone levels, risk of Cushing's syndrome
Rifampin Major Decreased fluticasone efficacy

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

โšก Moderate Interactions

  • Other corticosteroids
  • Anticholinergics

โ„น๏ธ Minor Interactions

  • None significant

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to fluticasone propionate or any excipients; untreated nasal infections.

๐Ÿ“Š Monitoring Parameters

Nasal symptoms, signs of adrenal suppression with prolonged use, growth in children.

๐Ÿคฑ Lactation Safety

Excretion in breast milk unknown; use with caution.

๐Ÿ’Š Overdose Management

Acute overdose unlikely; chronic overdose may lead to systemic corticosteroid effects; supportive care.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for alerflo nasal spray

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Alternative brands with exact same active ingredient (Fluticasone Propionate (27.5mcg)):

Medical Note: Always consult your doctor before switching medications.

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