aldol p 325mg/50mg tablet allopathy (Paracetamol/Acetaminophen (325mg) + Tramadol (50mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aldol p 325mg/50mg tablet allopathy (Paracetamol/Acetaminophen (325mg) + Tramadol (50mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Altar Pharmaceuticals Pvt Ltd. Contains Paracetamol/Acetaminophen (325mg) + Tramadol (50mg).

aldol p 325mg/50mg tablet - Uses, Price, Side Effects & Substitutes

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🏭 Altar Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aldol p 325mg/50mg tablet used for?

Acuvin Tablet (Paracetamol/Acetaminophen + Tramadol) is used to treat Moderate to severe pain. It contains Paracetamol/Acetaminophen (325mg) + Tramadol (50mg), which Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin sy. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paracetamol/Acetaminophen + Tramadol
  • Manufacturer: Altar Pharmaceuticals Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aldol p 325mg/50mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aldol p 325mg/50mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Paracetamol/Acetaminophen (325mg) + Tramadol (50mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Paracetamol/Acetaminophen + Tramadol
Brand NameAcuvin Tablet
ManufacturerAltar Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassPAIN ANALGESICS
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture and light
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionDistributed throughout body fluids; crosses placenta and enters breast milk.
Protein BindingParacetamol: 10-25%; Tramadol: 20%
MetabolismParacetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP2E1; Tramadol: Hepatic via CYP2D6 and CYP3A4 to active metabolite O-desmethyltramadol (M1).
Half-LifeParacetamol: 1.5-2.5 hours; Tramadol: 5-6 hours (M1: 7-9 hours)
ExcretionParacetamol: Renal (mostly as conjugates); Tramadol: Renal (90%) and feces (10%)
BioavailabilityParacetamol: 85-90%; Tramadol: 75%
Onset of ActionParacetamol: 30-60 minutes; Tramadol: 30-60 minutes
Peak Plasma TimeParacetamol: 0.5-2 hours; Tramadol: 1-2 hours
Duration of ActionParacetamol: 4-6 hours; Tramadol: 4-6 hours

Pharmacodynamics

Mechanism of ActionParacetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake.
Target ReceptorParacetamol: COX-1, COX-2 (central); Tramadol: Mu-opioid receptor, serotonin transporter, norepinephrine transporter
Pharmacodynamic EffectsAnalgesic, antipyretic (paracetamol); analgesic (tramadol)

💡 How and when to take aldol p 325mg/50mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture and light

⚙️ How aldol p 325mg/50mg tablet Works

Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake.

1 Paracetamol inhibits COX enzymes in the CNS, reducing prostaglandin synthesis and pain perception.
⬇️
2 Tramadol binds to mu-opioid receptors, activating G-protein coupled signaling and reducing pain transmission.
⬇️
3 Tramadol inhibits serotonin and norepinephrine reuptake, enhancing descending inhibitory pain pathways.
⬇️
4 Combination provides synergistic analgesic effect through complementary mechanisms.

💊 aldol p 325mg/50mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Moderate to severe pain, acute pain, postoperative pain

Off-label uses: Chronic pain, neuropathic pain (tramadol component)

⚠️ What are the side effects of aldol p 325mg/50mg tablet?

✅ Common Side Effects

  • Nausea
  • dizziness
  • drowsiness
  • constipation
  • headache
  • sweating

🚨 Serious Side Effects

  • Seizures
  • serotonin syndrome
  • respiratory depression
  • hepatotoxicity
  • hypotension
  • allergic reactions

⚠️ Rare Side Effects

  • QT prolongation
  • adrenal insufficiency
  • pancreatitis
  • toxic epidermal necrolysis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
MAOIs Major Risk of serotonin syndrome, hypertensive crisis
SSRIs Major Increased risk of serotonin syndrome
Warfarin Moderate Increased INR and bleeding risk
Alcohol Major Hepatotoxicity and CNS depression

🚨 Major Interactions

  • MAOIs
  • SSRIs
  • SNRIs
  • TCAs
  • Linezolid
  • Methylene blue
  • CNS depressants (alcohol, benzodiazepines)
  • Carbamazepine
  • Rifampin
  • Phenytoin

⚡ Moderate Interactions

  • Anticoagulants (warfarin)
  • Anticholinergics
  • Digoxin
  • Metoclopramide
  • Domperidone

ℹ️ Minor Interactions

  • Cholestyramine
  • Oral contraceptives

🍽️ Food Interactions

Food may delay absorption but not extent.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity with paracetamol; additive CNS depression with tramadol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, severe hepatic impairment, acute asthma, respiratory depression, MAOI use within 14 days, seizure disorders, acute intoxication with alcohol or CNS depressants

📊 Monitoring Parameters

Pain relief, respiratory rate, liver function tests, renal function, signs of serotonin syndrome

🤱 Lactation Safety

Paracetamol: Safe; Tramadol: Use with caution, monitor infant for sedation

💊 Overdose Management

Paracetamol: N-acetylcysteine; Tramadol: Naloxone (may increase seizure risk), supportive care

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

🛑 Myths vs. Facts about aldol p 325mg/50mg tablet

  • Myth: Generic substitutes of aldol p 325mg/50mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Paracetamol/Acetaminophen (325mg) + Tramadol (50mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aldol p 325mg/50mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

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