albez i 12mg/400mg tablet - Uses, Price, Side Effects & Substitutes
What is albez i 12mg/400mg tablet used for?
ABD Plus Tablet (Ivermectin + Albendazole) is used to treat Filariasis. It contains Ivermectin (12mg) + Albendazole (400mg), which Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ivermectin + Albendazole
- Manufacturer: Disan Pharma
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 albez i 12mg/400mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
albez i 12mg/400mg tablet का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Ivermectin (12mg) + Albendazole (400mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Ivermectin + Albendazole |
|---|---|
| Brand Name | ABD Plus Tablet |
| Manufacturer | Disan Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take albez i 12mg/400mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture
⚙️ How albez i 12mg/400mg tablet Works
Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells, causing hyperpolarization and paralysis; Albendazole: inhibits tubulin polymerization, disrupting microtubule formation and glucose uptake
💊 albez i 12mg/400mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Filariasis, strongyloidiasis, ascariasis, hookworm, trichuriasis, enterobiasis
Off-label uses: Scabies, lice, cutaneous larva migrans
⚠️ What are the side effects of albez i 12mg/400mg tablet?
✅ Common Side Effects
- Nausea
- vomiting
- diarrhea
- abdominal pain
- headache
- dizziness
🚨 Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- agranulocytosis
- seizures
⚠️ Rare Side Effects
- Alopecia
- acute renal failure
- pancreatitis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Theophylline | Major | Increased theophylline toxicity |
| Ketoconazole | Major | Increased ivermectin/albendazole levels |
| Rifampin | Moderate | Decreased albendazole levels |
| Grapefruit juice | Minor | Altered metabolism |
🚨 Major Interactions
- Warfarin
- Theophylline
- CYP3A4 inhibitors (e.g., ketoconazole)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampin)
- P-glycoprotein inhibitors
ℹ️ Minor Interactions
- Grapefruit juice
🍽️ Food Interactions
Fatty meal increases absorption of albendazole; avoid grapefruit juice
🍷 Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, pregnancy, lactation, hepatic impairment
📊 Monitoring Parameters
Liver function tests, renal function, blood counts
🤱 Lactation Safety
Not recommended; excreted in breast milk
💊 Overdose Management
Symptomatic and supportive; gastric lavage if recent
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose
🛑 Myths vs. Facts about albez i 12mg/400mg tablet
- Myth: Generic substitutes of albez i 12mg/400mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Ivermectin (12mg) + Albendazole (400mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of albez i 12mg/400mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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