Akglim-M 2 Tablet PR - Uses, Price, Side Effects
What is akglim-m 2 tablet pr used for?
Akglim-M 2 Tablet PR is a combination of Glimepiride and Metformin used to treat type 2 diabetes. Glimepiride stimulates insulin release, while Metformin reduces glucose production in the liver and improves insulin sensitivity, helping control blood sugar levels effectively.
- Generic Name: Glimepiride + Metformin
- Manufacturer: Akned Healthcare Pvt. Ltd.
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 akglim-m 2 tablet pr के बारे में संक्षिप्त जानकारी (Hindi Summary)
akglim-m 2 tablet pr का उपयोग मुख्य रूप से anti diabetic और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Glimepiride (2mg) + Metformin (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Glimepiride + Metformin |
|---|---|
| Brand Name | Amaryl M 1mg Tablet PR |
| Manufacturer | Akned Healthcare Pvt. Ltd. |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F); protect from moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
📅 When to take akglim-m 2 tablet pr?
💡 How and when to take akglim-m 2 tablet pr?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F); protect from moisture
⚙️ How akglim-m 2 tablet pr Works
Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: Decreases hepatic glucose production, increases insulin sensitivity
💊 akglim-m 2 tablet pr Uses in Hindi (Ke Fayde), Benefits & Indications
Type 2 diabetes mellitus when diet and exercise alone are inadequate
Off-label uses: Polycystic ovary syndrome (metformin component)
⚠️ What are the side effects of akglim-m 2 tablet pr?
✅ Common Side Effects
- Hypoglycemia
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
🚨 Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
- Pancreatitis
⚠️ Rare Side Effects
- Megaloblastic anemia
- Photosensitivity
- Disulfiram-like reaction
- Cholestatic jaundice
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Corticosteroids | Moderate | Reduced hypoglycemic effect |
| Alcohol | Moderate | Increased risk of lactic acidosis |
🚨 Major Interactions
- Insulin
- Other sulfonylureas
- Miconazole
- Phenylbutazone
- Alcohol
⚡ Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Clarithromycin
- Corticosteroids
- Diuretics
- NSAIDs
ℹ️ Minor Interactions
- Cimetidine
- Ranitidine
- Nifedipine
🍽️ Food Interactions
Food delays absorption of glimepiride; metformin absorption reduced by food
🍷 Alcohol Interaction
Increased risk of hypoglycemia and lactic acidosis
🛡️ Safety & Warnings
🚫 Contraindications
Type 1 diabetes, diabetic ketoacidosis, severe renal impairment (eGFR <30), hepatic impairment, hypersensitivity, acute conditions with risk of hypoxia
📊 Monitoring Parameters
Blood glucose, HbA1c, renal function (serum creatinine, eGFR), hepatic function, signs of lactic acidosis
🤱 Lactation Safety
Contraindicated; glimepiride excreted in milk, metformin excreted in milk
💊 Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose or IV dextrose; for metformin overdose, consider hemodialysis
⏰ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
🛑 Myths vs. Facts about akglim-m 2 tablet pr
- Myth: Generic substitutes of akglim-m 2 tablet pr are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Glimepiride (2mg) + Metformin (500mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of akglim-m 2 tablet pr can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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