ajapride m 1mg/500mg tablet pr - Uses, Price, Side Effects & Substitutes
What is ajapride m 1mg/500mg tablet pr used for?
Amaryl M 1mg Tablet PR (Glimepiride + Metformin) is used to treat Type 2 diabetes mellitus when diet and exercise alone are inadequate. It contains Glimepiride (1mg) + Metformin (500mg), which Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: D. Always consult your doctor before use. Take as prescribed.
- Generic Name: Glimepiride + Metformin
- Manufacturer: Ajanta Pharma Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 ajapride m 1mg/500mg tablet pr के बारे में संक्षिप्त जानकारी (Hindi Summary)
ajapride m 1mg/500mg tablet pr का उपयोग मुख्य रूप से anti diabetic और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Glimepiride (1mg) + Metformin (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Glimepiride + Metformin |
|---|---|
| Brand Name | Amaryl M 1mg Tablet PR |
| Manufacturer | Ajanta Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F); protect from moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take ajapride m 1mg/500mg tablet pr?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F); protect from moisture
⚙️ How ajapride m 1mg/500mg tablet pr Works
Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: Decreases hepatic glucose production, increases insulin sensitivity
💊 ajapride m 1mg/500mg tablet pr Uses in Hindi (Ke Fayde), Benefits & Indications
Type 2 diabetes mellitus when diet and exercise alone are inadequate
Off-label uses: Polycystic ovary syndrome (metformin component)
⚠️ What are the side effects of ajapride m 1mg/500mg tablet pr?
✅ Common Side Effects
- Hypoglycemia
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
🚨 Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
- Pancreatitis
⚠️ Rare Side Effects
- Megaloblastic anemia
- Photosensitivity
- Disulfiram-like reaction
- Cholestatic jaundice
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Miconazole | Major | Enhanced hypoglycemic effect |
| Alcohol | Major | Increased risk of lactic acidosis and hypoglycemia |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Beta-blockers | Moderate | Mask hypoglycemia symptoms |
| Corticosteroids | Moderate | Hyperglycemia |
| Diuretics | Moderate | Hyperglycemia |
| NSAIDs | Moderate | Enhanced hypoglycemic effect |
| Cimetidine | Minor | Increased metformin levels |
| Nifedipine | Minor | Increased metformin absorption |
🚨 Major Interactions
- Insulin
- Other sulfonylureas
- Miconazole
- Phenylbutazone
- Alcohol
⚡ Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Clarithromycin
- Corticosteroids
- Diuretics
- NSAIDs
ℹ️ Minor Interactions
- Cimetidine
- Ranitidine
- Nifedipine
🍽️ Food Interactions
Food delays absorption of glimepiride; metformin absorption reduced by food
🍷 Alcohol Interaction
Increased risk of hypoglycemia and lactic acidosis
🛡️ Safety & Warnings
🚫 Contraindications
Type 1 diabetes, diabetic ketoacidosis, severe renal impairment (eGFR <30), hepatic impairment, hypersensitivity, acute conditions with risk of hypoxia
📊 Monitoring Parameters
Blood glucose, HbA1c, renal function (serum creatinine, eGFR), hepatic function, signs of lactic acidosis
🤱 Lactation Safety
Contraindicated; glimepiride excreted in milk, metformin excreted in milk
💊 Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose or IV dextrose; for metformin overdose, consider hemodialysis
⏰ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
🛑 Myths vs. Facts about ajapride m 1mg/500mg tablet pr
- Myth: Generic substitutes of ajapride m 1mg/500mg tablet pr are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Glimepiride (1mg) + Metformin (500mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of ajapride m 1mg/500mg tablet pr can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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